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IRCT2014122020377N1 IRCT 2015-01-22 Zahedan University of Medical Sciences Comparsion of effectiveness of the bioadhesive pastes curcumin and topical corticosteroid for the treatment of oral lichen planus Comparison of effectiveness of the bioadhesive pastes curcumin and topical corticosteroid for the treatment of oral lichen planus 2014-12-16 anticipated 20 Complete https://irct.ir/trial/18073 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 Oral lichen planus. Intervention 1: Intervention group: Bioadhesive paste Containing curcumin 4 times per days 1h before meal and 20 minutes before sleep for 12 weeks. Intervention 2: control group receive oral past with triamsinolon 4 times per days 1h before meal and 20 minute before sleep for 12 weeks.
public Dr.Tahereh Nostatzehi
Oral medicine department, faculty of dentistry, Azadegan street,Zahedan
Zahedan Iran (Islamic Republic of) +95 433287991 nosratzehi@zaums.ac..ir Zahedan University of Medical Sciences scientific Dr.Tahereh Nosratzehi
Oral medicine department, faculty of dentistry, Azadegan street,Zahedan
Zahedan Iran (Islamic Republic of) +98 54 3328 7991 nosratzehi@zaums.ac.ir Zahedan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: older than 18 years of age Exclusion criteria: patient with systemic disease; pregnancy; smoking; lesion with displasia; those who received treatment for OLP at least 1 month previous to beginning the study; lesion adjacent to amalgam filling. 18 years 69 years Both l43 lichen planus Treatment - Drugs Treatment - Drugs Intervention group: Bioadhesive paste Containing curcumin 4 times per days 1h before meal and 20 minutes before sleep for 12 weeks control group receive oral past with triamsinolon 4 times per days 1h before meal and 20 minute before sleep for 12 weeks Size of lesion. Timepoint: The first week, Second week, First month, Third month. Method of measurement: With ruler and calpier. Level of pain. Timepoint: The first week , Second week , First month , Third month. Method of measurement: Use of Visual Analoge Scale (VAS) from 0- 10, 0: no pain and burning sensation and 10: sever pain and burning sensation. Zahedan University of Medical Sciences Approved 2014-12-15 Zahedan University of Medical Sciences Oral medicine department, faculty of dentistry, Azadegan street,Zahedan Zahedan Iran (Islamic Republic of)