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IRCT2015012520802N1 IRCT 2015-08-15 Vice chancellor for research,Islamic Azad University Pharmaceutical Branch of Tehran Herbal extract solution in treatment of seborrheic dermatitis Evaluation of the effect and safety of herbal extracts anti dandruff formulation comparing with clotrimazole lotion in patients with seborrheic dermatitis referring to the clinic of center for research and training in skin diseases and leprosy during the year 1394 2015-08-23 anticipated 20 Complete https://irct.ir/trial/18393 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Seborrheic Dermatitis. Intervention 1: Volunteers in the intervention group use the anti dandruff lotion with herbal extracts twice a day for 4 weeks,1 cc per consumption topical on their scalp. Intervention 2: Volunteers in the control group use clotrimazole lotion 1 cc twice daily for 4 weeks, topically on their scalp.
public Dr Hamid Reza Ahmadi Ashtiani
Pharmaceutical Sciences Branch of Islamic Azad University, Yakhchal St, Shariati Ave.
Tehran Iran (Islamic Republic of) +98 21 2264 0051 ahmadi@iaups.ac.ir Pharmaceutical Sciences Branch of Islamic Azad University scientific Dr Hamid Reza Ahmadi Ashtiani
Pharmaceutical Sciences Branch of Islamic Azad University, Yakhchal St, Shariati Ave.
Tehran Iran (Islamic Republic of) +98 21 2248 0233 ahmadi@iaups.ac.ir Pharmaceutical Sciences Branch of Islamic Azad University Iran (Islamic Republic of) Inclusion criteria: male patients; healthy general condition; clinically diagnosed seborrheic dermatitis; 20-30 years old; consent form signed by patients. Exclusion criteria: use of topical steroids during 2 weeks ago; use of topical retinoids during 2 weeks ago; use of topical antifungals during 2 weeks ago; use oftopical anti-inflammatory druds during 2 weeks ago; use of topical antibiotics and any other topical treatments for seborrheic dermatitis like anti-dandruff shampoo and coal tar during 2 weeks ago; use of systemic anti-fungals during the last month; use of systemic steroids during the last month; use of systemic antibiotic during the last month; use of systemic anti-inflammatory drugs and immunomodulator drugs during the last month; use oral retinoid during last 6 months; history of hypersensitivity to azoles or herbal compound of our solution; comorbidities(AIDS,Parkinson,diabetes,…); skin disease like psoriasis, acne, … 20 years 30 years Male L21.8 Other seborrhoeic dermatitis Treatment - Drugs Treatment - Drugs Volunteers in the intervention group use the anti dandruff lotion with herbal extracts twice a day for 4 weeks,1 cc per consumption topical on their scalp Volunteers in the control group use clotrimazole lotion 1 cc twice daily for 4 weeks, topically on their scalp Scalp sebum. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: Sebometer. Scalp PH. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: PH meter. Dandruff. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: Pixel. Erythema and itching. Timepoint: Begining of the study,2 weeks and 4 weeks after treatment. Method of measurement: Clinical examination, Questionnaire. Vice chancellor for research,Islamic Azad University Pharmaceutical Branch of Tehran Approved 2015-04-18 Ethics Committee of centre for research and training in skin disease and leprosy 415,Taleghani st Tehran Iran (Islamic Republic of)