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IRCT2015031421460N1 IRCT 2015-08-01 Vice Chancellor for research of Fasa University of Medical Sciences Hyaluronic Acid Compared with Corticosteroid Injections for the Treatment of Osteoarthritis of the knee Hyaluronic Acid Compared with Corticosteroid Injections for the Treatment of Osteoarthritis of the knee 2015-05-05 anticipated 140 Complete https://irct.ir/trial/18802 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 Knee Osteoarthritis. Intervention 1: Patients participating in the study will be divided into two groups of 70 people. One group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic physician. And second group will take hyaluronic acid (Hyalgan) in 2 ml vials to the space between the knee joint by an orthopedic physician. Intervention 2: intervention group: hyaluronic acid (Hyalgan) in 2 ml vials to the space between the knee joint by an orthopedic physician. Intervention 3: control group: this group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic physician.
public Dr. Alireza Askari
Fasa University of Medical Sciences, Ebne Sina squar, Fasa, Fars
Fasa Iran (Islamic Republic of) +98 71 5335 0994 aaskari60@yahoo.com Fasa University of Medical Sciences scientific Dr. Alireza Askari
Fasa University of Medical Sciences, Ebne Sina square, Fasa, Fars
Fasa Iran (Islamic Republic of) +98 71 5335 0994 aaskari60@yahoo.com Fasa University of Medical Sciences Iran (Islamic Republic of) Qualified patients were men and women from 45 years to 80 years of age suffering from knee OA for more than 3 months, with radiographic. Main exclusion criteria were a history or presence of trauma or surgery or cancer or malignant tumors, infections and sores on the target knee, History of vasovagal shock , The use of NSAIDs in 2 days prior to injection, Any receiving corticosteroids injection in the knee in the last 6 months , Pregnancy and lactation 48 years 13 years Both M17- M18- Gonarthrosis [arthrosis of knee] Treatment - Drugs Treatment - Drugs Treatment - Drugs Patients participating in the study will be divided into two groups of 70 people. One group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic physician. And second group will take hyaluronic acid (Hyalgan) in 2 ml vials to the space between the knee joint by an orthopedic physician. intervention group: hyaluronic acid (Hyalgan) in 2 ml vials to the space between the knee joint by an orthopedic physician control group: this group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic physician Pain. Timepoint: before intervention- one- two- three months after intervention. Method of measurement: Visual analogue scale and questionnaire. Physical function. Timepoint: before and after intervention. Method of measurement: questionnaire and interview with patients. Vice Chancellor for research of Fasa University of Medical Sciences Approved 2014-12-02 Ethics Committee of Fasa University of Medical Sciences Fasa University of Medical Sciences, Ebne Sina square, Fasa, Fars Fasa Iran (Islamic Republic of)