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IRCT2017062421719N1 IRCT 2017-08-16 Mohaghegh Ardabili University The effect of exercise training with ingested of vitamin D on angiogenesis Investigate and Compare the Effect of Eight Weeks Resistance and Endurance Training with Vitamin D Supplementation on Some Serum Angiogenesis Indices in Obese Hypertensive Meedle- Aged Men 2016-04-20 anticipated 63 Complete https://irct.ir/trial/18958 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Factorial, Purpose: Prevention. N/A Hypertension. Intervention 1: The subjects of resistance exercise with vitamin- D group participated in 8 weeks of resistance training with ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week. Intervention 2: The subjects of endurance exercise with vitamin- D group participated in 8 weeks of endurance training with ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week. Intervention 3: The subjects of endurance exercise with placebo group participated in 8 weeks of endurance training with ingested of placebo. Blood sample were taken in basal state and after 8 week. Intervention 4: The subjects of resistance exercise with placebo group participated in 8 weeks of resistance training with ingested of placebo. Blood sample were taken in basal state and after 8 week. Intervention 5: The subjects of vitamin- D group participated in 8 weeks of ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week. Intervention 6: The subjects of control group (There was no intervention). Blood sample were taken in basal state and after 8 week.
public Mehdi Hakimi
Mohaghegh Ardabili University, University Street, Ardabil
Ardabil Iran (Islamic Republic of) +98 45 3150 5625 Mehdihakimi@uma.ac.ir Mohaghegh Ardabili University scientific Marefat Siahkuhian
Mohaghegh Ardabili University, University Street, Ardabil
Ardabil Iran (Islamic Republic of) +98 45 3150 5625 m_siahkohian@uma.ac.ir Mohaghegh Ardabili University Iran (Islamic Republic of) Inclusion criteria: non-athletic, Being in the age range of 35 to 45 years old, Being male, obesity and having high blood pressure (subjects were on the threshold of having hypertension, but not taking the drug that reduce blood pressure). Exclusion criteria: Taking the drug that reduce blood pressure and smoking, 35 years 45 years Male I10 Essential (primary) hypertension Prevention Prevention Prevention Prevention Prevention N/A The subjects of resistance exercise with vitamin- D group participated in 8 weeks of resistance training with ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week. The subjects of endurance exercise with vitamin- D group participated in 8 weeks of endurance training with ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week The subjects of endurance exercise with placebo group participated in 8 weeks of endurance training with ingested of placebo. Blood sample were taken in basal state and after 8 week. The subjects of resistance exercise with placebo group participated in 8 weeks of resistance training with ingested of placebo. Blood sample were taken in basal state and after 8 week. The subjects of vitamin- D group participated in 8 weeks of ingested of vitamin- D supplement. Blood sample were taken in basal state and after 8 week. The subjects of control group (There was no intervention). Blood sample were taken in basal state and after 8 week. Endothelial growth factor. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Nitric oxaide. Timepoint: Basal state and after 8 week. Method of measurement: Based on micromole per liter with ELISA method. Interleukin- 8. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Interleukin- 4. Timepoint: Based on nanogram per liter with ELISA method. Method of measurement: Basal state and after 8 week. Blood pressure. Timepoint: Basal state and after 8 week. Method of measurement: Based on millimeters of mercury using a digital arm manometer. Mohaghegh Ardabili University Approved 2016-08-27 Mohaghegh Ardabili University Mohaghegh Ardabili University, University Street, Ardabil Ardabil Iran (Islamic Republic of)