]>
IRCT2015042721955N2 IRCT 2015-08-02 Babol University of Medical Sciences A Comparison psycho-sexual therapy and pharmacotherapy Bupropion interventions on improvement of sexual function in infertile women - A Comparison of the effect psycho-sexual therapy and pharmacotherapy Bupropion interventions on improvement of sexual function in infertile women 2015-01-01 anticipated 99 Complete https://irct.ir/trial/19072 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: -. 2-3 Sexual Dysfunction. Intervention 1: Psycho-sexual therapy group: This group will participate in a two-hour group session for 10 weeks. Each group consists of 8–12 members. Therapeutic model is a combination of mind fullness-Based cognitive therapy and sexual skills. Sexual behavioral program is based on Crowe and Ridley model. Intervention 2: Pharmacotherapy group: This group will take a tablet of Bupropion SR (150 mg) daily (evening) (manufactured by D Abidi plant) for two months by a psychiatrist. Subjects will receive 30 tablets after the interview, and will refer to center monthly to receive their medication. Duration of treatment will be two months. Intervention 3: Control group: Participants in this group will complete questionnaires at the beginning of the study and two months afterward. In order to observe the ethics of research, members of this group will be referred to sex therapy clinic at the end of two months of treatment. All groups will complete questionnaires in the beginning and ending of the study.
public Hajar Pasha
Midwifery Department, Babol University of Medical Sciences, Ganjafrouze Street, Mazandaran Province, Iran
Babol Iran (Islamic Republic of) 4717647745 +98 11 3219 0597 h.pasha@mubabol.ac.ir; pashahajar@yahoo.com; dhajarpasha@gmail.com Babol University of Medical Sciences scientific Zahra Basirat
Fatemeh Alzahra Infertility and Reproductive Health Research Center of the Babol University of Medical Sciences, Tork Mahalleh, Babol, Mazandaran province, Iran
Babol Iran (Islamic Republic of) 4717647745 +98 11 3219 0597 basiratzahra@yahoo.com Fatemeh Alzahra Infertility and Reproductive Health Research Center of the Babol University of Medic Iran (Islamic Republic of) Inclusion criteria included: The less or equal score of 26.55 from Female Sexual Function Index(FSFI); The final diagnosis with clinical interview is based on DSM-V criteria by psychologist; duration of infertility more than 1 year; women infertile who did not decide to undergo fertility treatment until 2 months afterward; aged between 15-45 years; ability to read and to write; having a stable sexual activity(at least for recent four weeks); availability of the husband; no remarrying of couples; no history of sterilization; no foster child. Exclusion criteria included: drug abuse; severe psychiatric disorders(major depression, bipolar disorder, patients with suicidal idea or psychosis); history of physical illness(diabetes mellitus, cardiovascular diseases, hypertension, hyperthyroidism, hypothyroidism, epilepsy, hepatic dysfunction); physical problems(spinal cord injury, limb deformity); mental health problems under the treatment of a physician; drugs consumers causing sexual dysfunction such as barbiturates, benzodiazepines , antidepressants, ant hypertensions; having psychological support( psychotherapy sessions, relaxation techniques, yoga ); experiencing a stressful event in the past three months(death or serious illness in the family, a major change in living conditions). 15 years 45 years Female F52 Sexual dysfunction, not caused by organic disorder or disease Treatment - Other Treatment - Drugs N/A Psycho-sexual therapy group: This group will participate in a two-hour group session for 10 weeks. Each group consists of 8–12 members. Therapeutic model is a combination of mind fullness-Based cognitive therapy and sexual skills. Sexual behavioral program is based on Crowe and Ridley model. Pharmacotherapy group: This group will take a tablet of Bupropion SR (150 mg) daily (evening) (manufactured by D Abidi plant) for two months by a psychiatrist. Subjects will receive 30 tablets after the interview, and will refer to center monthly to receive their medication. Duration of treatment will be two months. Control group: Participants in this group will complete questionnaires at the beginning of the study and two months afterward. In order to observe the ethics of research, members of this group will be referred to sex therapy clinic at the end of two months of treatment. All groups will complete questionnaires in the beginning and ending of the study. Sexual function. Timepoint: Before and two months after of intervention. Method of measurement: Female Sexual Function Index (FSFI), and clinical interview based on the diagnostic criteria of DSM-V. Depression, Anxiety, General health, Sleep Quality, Couple Burnout, Body Image. Timepoint: Before and two months after of intervention. Method of measurement: Beck Depression Inventory (BDI), Spielberger State-Trait Anxiety Inventory (STAI), General health questionnaire (GHQ), Pittsburgh Sleep Quality Index (PSQI), Couple Burnout Measurement (CBM), and Body Image Assessment, and clinical interview based on the diagnostic criteria of DSM-V. Babol University of Medical Sciences Approved 2014-12-10 The Ethics Committee of Babol University of Medical Sciences Babol University of Medical Sciences, Ganjafrouze Street, Mazandaran Province, Iran Babol Iran (Islamic Republic of)