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IRCT2015060722584N1 IRCT 2015-09-07 Shiraz university of medical science The efficacy of Cuscuta Chinensis on depression Comparison of the efficacy of Cuscuta Chinensis versus Fluoxetine on depression in cases with major depression 2015-04-22 anticipated 60 Complete https://irct.ir/trial/19458 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Double blind included patients and researchers. 3 Depression. Intervention 1: 500 mg powder of Fluoxetine ( Exir ) capsules twice in day for 6 weeks. Intervention 2: 500mg Cuscuta capsule twice in day for 6 weeks.
public Azade kiani
Faculty of Iranian Medicine, Faculty of Medicine, Setad
Shiraz Iran (Islamic Republic of) +7 132332366 Kiania@sums.Ac.irKianiazade@yahoo.com Shiraz University of Medical Science scientific Ali Firozabadi
Building Number 2, Faculty of Med,setad
Shiraz Iran (Islamic Republic of) +98 71 3233 7589 Firozabadiali@sums.ac.ir Shiraz University of Medical Science Iran (Islamic Republic of) Inclusion: patients over 18 with the diagnosis of depression based on DSM5 and Beck criteria, patients with written informed consent. Exclusion: Other underlying psychological disorder like Schizophrenia, schizoaffective, bipolar disorder, psychotic disorder, organic disorder make depression directly like hypothyroidism, pregnancy lactation, addiction, patients with suicidal thought and the patients. Who may need electronic convulsive therapy (ECT), being under the treatment of antidepressant on 1 month ago, chronic respiratory disease and past history of drug reaction to Cuscuta. 18 years 80 years Both F32 Depressive episode Treatment - Drugs Treatment - Drugs 500 mg powder of Fluoxetine ( Exir ) capsules twice in day for 6 weeks 500mg Cuscuta capsule twice in day for 6 weeks Depression. Timepoint: baseline , after intervention on second,4th and 6th week. Method of measurement: Beck depression inventory. Side effect like unusual drug reaction, GI discomfort. Timepoint: During the clinical trial specially on second,4th and 6th week. Method of measurement: By asking the patients. Shiraz university of medical science Approved 2015-04-20 Ethics committee of Shiraz University of Medical Sciences Vice chancellor for research, Shiraz University of Medical Sciences, Zand St. Shiraz Iran (Islamic Republic of)