IRCT2017102022689N5 IRCT 2017-11-05 Vice chancellor for research and technology, Tehran university of medical sciences The effect of Cynara Scolymus on hyperlipidemia To determine the effectiveness of Cynara Scolymus extract on lipid profile of hemodialysis patients compared with placebo 2017-11-21 anticipated 40 Complete https://irct.ir/trial/19517 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 3 End stage renal disease. Intervention 1: In the intervention group, the samples receive artichoke capsules ( 320 mg) up to 6 weeks twice daily ( 8 am and 8 pm ). All samples in both intervention and control groups, routinely receive atorvastatin tablets and low salt diet. The samples will be asked not to change in their diet and physical activity during this study and inform researchers about any changes in their medications. Intervention 2: In the placebo group, the samples receive placebo capsule containing starch ( 320 mg) up to 6 weeks twice daily ( 8 am and 8 pm ). All samples in both intervention and control groups, routinely receive atorvastatin tablets and low salt diet. The samples will be asked not to change in their diet and physical activity during this study and inform researchers about any changes in their medications.