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IRCT2015061422738N1 IRCT 2016-01-17 Deputy of Research and Technology, Birjand University of Medical Sciences The Effect of Phytochemicals on the treatment of Phlebitis The effect of Quercetin and Tannic acid on the treatment of phlebitis caused by venous catheters 2015-10-23 anticipated 120 Complete https://irct.ir/trial/19549 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Factorial, Purpose: Treatment. N/A phlebitis. Intervention 1: Use of Placebo (cream base) in the control group for 72 hours in 12-hour intervals in the area of phlebitis. Intervention 2: Use of Tannic acid 7% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis. Intervention 3: Use of Quercetin 2% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis. Intervention 4: Use the combination of Quercetin 2% and Tannic acid %7 in an intervention group for 72 hours in 12-hour intervals in the area of phlebitis.
public Mohsen Foadoddini
Ghaffari street
Birjand Iran (Islamic Republic of) 9717853577 +98 56 3239 5861 foadmohsen@yahoo.com foadoddini@bums.ac.ir Birjand University of Medical Sciences scientific Mohsen Foadoddini
Birjand University of Medical Sciences
Birjand Iran (Islamic Republic of) 971785577 +98 56 3239 5168 foadoddini@bums.ac.ir s.ghorbani@bums.ac.ir rezamood@yahoo.com Birjand University of Medical Sciences Iran (Islamic Republic of) IInclusion criteria: having an IV catheter, gauge No. 20 (with all catheters of an essentially single brand), age between 18-60 years old, hospitalization in the internal medicine ward for at least 72 hours, no allergy to the drugs and the wound dressing, lack of blood transfusion, systolic blood pressure between 90 to 180 mmHg, no diabetes, no skin disease in the area of phlebitis, no pregnancy or lactation, having at least one phlebitis symptom (pain, redness, irritation) around the area, no chemical or herbal oil use for treatment of the phlebitis during the study, no history of allergy to the plants containing Quercetin or Tannic acid, using upper limbs for catheterization, using aseptic conditions for catheterization Exclusion criteria: patients discharged before three days, taking contraceptive drugs, patients with known comorbidities including hyper-coagulability states (e.g., anti-cardiolipin antibodies, anti-phospholipid antibodies, and vitamin C deficiency) 18 years 60 years Both T80.1 Vascular complications following infusion, transfusion and therapeutic injection Placebo Treatment - Drugs Treatment - Drugs Treatment - Drugs Use of Placebo (cream base) in the control group for 72 hours in 12-hour intervals in the area of phlebitis Use of Tannic acid 7% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis Use of Quercetin 2% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis Use the combination of Quercetin 2% and Tannic acid %7 in an intervention group for 72 hours in 12-hour intervals in the area of phlebitis Phlebitis. Timepoint: Before and 12 hours after treatment for 72 hours. Method of measurement: 4 degree visual phlebitis scale. Dermal side effects. Timepoint: 12 hours for 72 hours. Method of measurement: Observation. Deputy of Research and Technology, Birjand University of Medical Sciences Approved 2015-06-08 Birjand University of Medical Sciences Ayatollah Ghaffari Street, Birjand University of Medical Sciences, Birjand Iran (Islamic Republic of)