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IRCT2282620150719N1 IRCT 2015-07-19 Shiraz University of Medical Sciences Effect of combined of supplement with carnitine and coenzyme Q10, versus therapeutic lifestyle changes (TLC Diet) diet on myocardial infarction patients. Therapeutic Lifestyle Changes Diet (TLC) Evaluation of effects of combined of supplement with carnitine and coenzyme Q10, versus therapeutic lifestyle changes (TLC Diet) diet on cardiovascular risk factors, function and quality of life after angioplasty in patients with experience of myocardial infarction 2015-05-09 anticipated 128 Complete https://irct.ir/trial/19603 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Factorial, Purpose: Supportive. N/A myocardial infarction. Intervention 1: control group: without any intervention, patient receive routine care. Intervention 2: Diet and supplement group: patient receive therapeutic life style change diet and two supplement , l-carnitin with dose 1200 mg , co- Q10 with dose 150 mg. Intervention 3: Diet group: patient receive therapeutic life style change diet suitable with weight and individual properties. Intervention 4: supplement group: patient receive two supplement , l-carnitin with dose 1200 mg , co- Q10 with dose 150 mg.
public Mohammad Hassan Eftekhari
Blov modarres, Blov razi,School of Nutrition and Food Sciences
Shiraz Iran (Islamic Republic of) 71645-111 +98 71 3725 1001 h_eftekhar@yahoo.com Shiraz University of Medical Sciences scientific Mohammad Hassan Eftekhar
Blov.modaress,Blov. razi, School of Nutrition and Food Sciences
Shiraz Iran (Islamic Republic of) 71645111 +98 71 3725 7288 h_eftekhar@yahoo.com School of Nutrition and Food Science Iran (Islamic Republic of) inclusion criteria: first experience of myocardial infarction; age between 40 -65; candidate for angioplasty revascularization; LDL >130؛ without anti lowering lipid six month ago; ejection fraction between 30-60; receive atorvastatin 80 mg daily; exclusion criteria: allergy with atorvastatin; history of cardiac event after angioplasty; patient with arrhythmia or congestive heart failure; history of consumption of antioxidant such as vitamin C, E and omega 3; history of consumption warfarin; history of documented psychological disease ; leave the patient before 60 days after intervention in RCT; 40 years 65 years Both I21 Acute myocardial infarction Other Treatment - Other Lifestyle Treatment - Other control group: without any intervention, patient receive routine care Diet and supplement group: patient receive therapeutic life style change diet and two supplement , l-carnitin with dose 1200 mg , co- Q10 with dose 150 mg Diet group: patient receive therapeutic life style change diet suitable with weight and individual properties supplement group: patient receive two supplement , l-carnitin with dose 1200 mg , co- Q10 with dose 150 mg LDL. Timepoint: 24 hours after myocardial infarction than 3 month after intervention. Method of measurement: enzymatic method calculate. Quality of life. Timepoint: 10 days after myocardiad in farction. Method of measurement: MacNew questionaire. Ejection fraction. Timepoint: 24 houre after myocardiad in farction. Method of measurement: echocardiography by specilalist. Triglyceride (TG). Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: Photometric method. High-density lipoprotein (HDL). Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: Photometric method. Physical Activity. Timepoint: 7 days before myocardial infarction then 3 month after intervention. Method of measurement: Intinternational Physical Activity Questionnaire - Short Form (IPAQ-SF). H- CRP. Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: ELISA by micropipette reader. IL-6. Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: ELISA. Shiraz University of Medical Sciences Approved 2015-04-19 Shiraz UniversityMedical Sciences Zand Blov,Shiraz University Medical Sciences Shiraz Iran (Islamic Republic of)