]>
IRCT2015070623099N1 IRCT 2015-10-18 Mashhad University of Medical Sciences, School of Pharmacy Cyproheptadine effect on insomnia and loss of appetite caused by methylphenidate in ADHD children Evaluate the effectiveness of cyproheptadine on prevention of sleep disorders and appetite caused by the consumption of methylphenidate in children with ADHD and its effects on the efficiency of methyl Fndyt 2015-04-12 anticipated 60 Complete https://irct.ir/trial/19787 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 3 Attention deficit hyperactivity disorder. Intervention 1: Intervention Groups: cyproheptadine, tablets 4 mg, orally, two half a tablet twice a day for 2 months. Intervention 2: In the control group: placebo, tablet, taken orally, once daily for two months.
public Faeze Kadkhoda Mezerji
College of Pharmacy, Ferdowsi University campus, Vakil Abad Blvd, Mashhad
Mashhad Iran (Islamic Republic of) +98 51 3893 6424 kadkhodaf891@mums.ac.ir Mashhad University of Medical Sciences - School of Pharmacy scientific Dr. Sepide Elyasi
College of Pharmacy, Ferdowsi University campus, Vakil Abad Blvd, Mashhad
Mashhad Iran (Islamic Republic of) +98 51 3882 3255 elyasis@mums.ac.ir Mashhad University Of Medical Siences Iran (Islamic Republic of) Inclusion criteria: patient satisfaction; age older than 3 years old; no use of concomitant medications that have a significant impact on sleep or appetite. Exclusion criteria: the risk of renal failure; the risk of cardiovascular diseases; the risk of thyroid diseases; sensitivity to cyproheptadine; intolerance side effects. 2 years 12 years Both F90.0 Disturbance of activity and attention Treatment - Drugs Treatment - Drugs Intervention Groups: cyproheptadine, tablets 4 mg, orally, two half a tablet twice a day for 2 months In the control group: placebo, tablet, taken orally, once daily for two months. Weight. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: In kilograms and is using the Digital Scale. Height. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Measured in meters. Growth rate. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: In grams per day. Changes in sleep by PSQI scale. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Using PSQI questionnaire. Dry mouth. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Swelling. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Sleepiness during the day. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Gastrointestinal side effects (diarrhea, nausea, vomiting and abdominal pain). Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Skin reactions. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Methylphenidate trade name. Timepoint: Baseline; second week; forth week; sixth week; eighth week. Method of measurement: Questionnaire. Mashhad University of Medical Sciences, School of Pharmacy Approved 2015-06-06 Mashhad University of Medical Sciences College of Pharmacy, Ferdowsi University campus, Vakil Abad Blvd, Mashhad Mashhad Iran (Islamic Republic of)