]>
IRCT2015081423426N1 IRCT 2015-09-08 Bahram Mofid The effect of processed honey and royal jelly on cancer-related fatigue -- Evaluation of the effect of processed honey and royal jelly on cancer-related fatigue: a double blind randomized clinical trial. 2012-03-08 anticipated 52 Complete https://irct.ir/trial/19969 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: randomization were done with using block randomization. N/A Neoplasms. Intervention 1: Intervention group 1: 26 patients received processed honey and royal jelly. Processed honey and royal jelly, made under standard-state conditions with the permission of food and drug organization of ministry of health and medical education of Iran. The intervention group were instructed to consume their supplement 5mL twice daily for 4 weeks. They were assessd at the beginning of study, after 2 weeks, and then at the end of 4 weeks of treatment. Intervention 2: Control group : 26 patients received pure honey . Pure honey , made under standard-state conditions with the permission of food and drug organization of ministry of health and medical education of Iran. The control group were instructed to consume their supplement 5mL twice daily for 4 weeks. They were assessd at the beginning of study, after 2 weeks, and then at the end of 4 weeks of treatment.
public Bahram Mofid
Shohada-e-Tajrish Hospital, Department of Radiation Oncology
Tehran Iran (Islamic Republic of) +98 21 2272 8081 mofid429@yahoo.com Shahid Beheshti University of Medical Sciences, Tehran, Iran scientific Amir Shahram Yousefi Kashi
Shohada-e-Tajrish Hospital, Department of Radiation Oncology
Tehran Iran (Islamic Republic of) +98 21 2271 5739 shahpoo2002@yahoo.com Shahid Beheshti University of Medical Sciences, Tehran, Iran Iran (Islamic Republic of) Inclusion criteria: age more than 18; having the diagnosis of a solid (non-hematologic) malignancy; visual analogue scale (VAS) more than 4; Karnofsky Performance Status (KPS) more than 70; serum hemoglobin level of more than 8g/dL with no abrupt decrease (more than 2g/dl) during the last month; Liver enzymes not more than three times above the normal limits; serum total bilirubin less than 2mg/dL; serum creatinine less than 2mg/dL and creatinine clearance more than 60ml/mi. Exclusion criteria: Patients with hypersensitivity to honey, uncontrolled cardiac or respiratory problems; any other serious medical condition, including severe infection or uncontrolled pain; pregnancy, major depression; taking medications with potential effects on fatigue; such as psychiatric medication (anti-depressants; psychostimulants,etc) or growth factors like erythropoietin. 18 years 100 years Both C15, C16, --- Treatment - Drugs Placebo Intervention group 1: 26 patients received processed honey and royal jelly. Processed honey and royal jelly, made under standard-state conditions with the permission of food and drug organization of ministry of health and medical education of Iran. The intervention group were instructed to consume their supplement 5mL twice daily for 4 weeks. They were assessd at the beginning of study, after 2 weeks, and then at the end of 4 weeks of treatment. Control group : 26 patients received pure honey . Pure honey , made under standard-state conditions with the permission of food and drug organization of ministry of health and medical education of Iran. The control group were instructed to consume their supplement 5mL twice daily for 4 weeks. They were assessd at the beginning of study, after 2 weeks, and then at the end of 4 weeks of treatment. Cancer-related fatigue. Timepoint: Before intervention, 2 Weeks after intervention and 4 weeks after intervention. Method of measurement: Fatigue Severity Scale. --. Timepoint: --. Method of measurement: --. -- -- Bahram Mofid Approved 2012-03-08 Ethics committee of Shahid Beheshti University of Medical Sciences 2nd Shahid Beheshti University of Medical Sciences Bldg. ,Next to Ayatollah Taleghani Hospital, Evin Tehran Iran (Islamic Republic of)