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IRCT2015080523517N1 IRCT 2017-04-15 Mazandaran University of Medical Sciences The effects of intravenous morphine sulfate with ketamine in renal pain. A Comparison, between the analgesic effects of intravenous morphine sulfate with ketamine regimen, and intravenous morphine sulfate regimen solely,in management of the acute pain in renal colic patients who admitted to the emergency department of Imam Khomeini hospital of Sari in year 1394 2015-09-20 anticipated 200 Complete https://irct.ir/trial/20034 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Renal colic. Intervention 1: Morphine sulfate with 0.1 mg / kg the time of intervention and if necessary 0.05 mg / kg in 20 minute after intervention in both control and experimental groups. Intervention 2: Ketamine 0.2 mg/kg before the time of intervention in experimental group. Intervention 3: Placebo(normal salin) 5 ml at the time of intervention in control group.
public Salman Erfanian Irankar
Imam Khomeini hospital
Sari Iran (Islamic Republic of) 00981133361700 +98 11 3336 1700 s.erfanian@mazums.ac.ir Mazandaran University of Medical Sciences scientific Seyyed Mohammad Hosseininejad
Imam Khomeini hospital
Sari Iran (Islamic Republic of) +98 11 3336 1700 mhoseininejad@mazums.ac.ir Mazandaran University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: All patients with acute renal colic with VAS pain score between 7 and 10. Exclusion criteria: Pregnancy or probable pregnancy; Breast feeding; Contraindications for Morphine usage; History of opium addiction; Taking any analgesics during last 6 hours prior of admission; Peritoneal signs and symptoms in abdominal examination; History of cardiovascular diseases; Psychosis; Refusal of the patients from the participation. 18 years 55 years Both N23 Unspecified renal colic Treatment - Drugs Treatment - Drugs Treatment - Drugs Morphine sulfate with 0.1 mg / kg the time of intervention and if necessary 0.05 mg / kg in 20 minute after intervention in both control and experimental groups Ketamine 0.2 mg/kg before the time of intervention in experimental group Placebo(normal salin) 5 ml at the time of intervention in control group Pain. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Visual analogue scale. Respiratory rate. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Respiratory rate in minute. Nausea. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Positive/negative. Vomiting. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Positive/negative. Vertigo. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Positive/ negative. Blood pressure. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: mmHg. Rash or hives. Timepoint: Zero, 20 and 40 minute after intervention. Method of measurement: Positive/ negative. Mazandaran University of Medical Sciences Approved 2017-04-09 Mazandaran University of Medical Sciences Jouybar crosssroad Sari Iran (Islamic Republic of)