<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT2015080823554N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2015-09-28</date_registration>
      <primary_sponsor>Research Center School of Nursing and Midwifery, Tehran</primary_sponsor>
      <public_title>The effect of acupressure on fatigue and quality of life of asthmatic pation</public_title>
      <acronym></acronym>
      <scientific_title>Effect of acupressure on severity of fatigue and quality of life of asthmatic pation</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2015-05-10</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>72</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/20069</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive.</study_design>
      <phase>N/A</phase>
      <hc_freetext>asthma.</hc_freetext>
      <i_freetext>Intervention 1: Patients in the control group routine care referral center include the period (2 months) under the doctor's clinic and receive medication adjustments. Intervention 2: Patients in the experimental group received acupressure also receive routine care center. In the experimental group, Chinese acupressure on the ST36 (in the anterior part of the leg and within the width of a finger spines anterior tibia), SP6 (the medial tibia posterior side of the leg above the medial malleolus), GB34 (in the inferior frontal troughs the fibula bone), LU1 (in the chest outside the chest and in the intercostal space), KI1 (in the soles of the feet are 3/1 and 3/2 imaginary line between the second and third toes and heel) in sides for 2 minutes per point (1 minute direct pressure with the thumb until the person feels pain, distention, and more with the same amount of flow and pressure 1 minute massage is done in a clockwise direction) total 20-minute massage per person, 3 days per week for 8 weeks on patients there.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan></results_IPD_plan>
      <results_IPD_description></results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Shadan Pedramrazi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faculty of Nursing &amp; Midwifery, Tohid square</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 21 6693 7120</telephone>
        <email>pedramrazi@tums.ac.ir</email>
        <affiliation>Tehran University of Medical Sciences,School of Nursing and Midwifery</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Shadan Pedramrazi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faculty of Nursing &amp; Midwifery, Tohid square, Nosrat Eastern St</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 21 6693 7120</telephone>
        <email>pedramrazi@tums.ac.ir</email>
        <affiliation>Tehran University of Medical Sciences,School of Nursing and Midwifery</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>- Inclusion criteria:&#13;
In this study, all subjects in addition to the informed consent must also meet the following conditions.&#13;
1) younger than 65 and older than 18 years.&#13;
2) have an incentive to participate in the study.&#13;
3) The disease is confirmed by the medical experts and the results of diagnostic tests.&#13;
4) lowering medications such as amantadine not use fatigue.&#13;
5) disease is not known psychological and psychiatric drugs affecting their consumption.&#13;
6) the ability to understand their conversation in Farsi.&#13;
7) are literate.&#13;
8) the possibility of establishing direct telephone contact with the patients' residence there.&#13;
- Exclusion criteria:&#13;
1) consent to continue participating in each stage of intervention.&#13;
2) the absence of the patient in the two sessions of acupressure&#13;
3) During the study, the disease progresses or the patient dies.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>65 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria></exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>J45.0</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Predominantly allergic asthma</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Patients in the control group routine care referral center include the period (2 months) under the doctor's clinic and receive medication adjustments.</i_keyword>
      <i_keyword>Patients in the experimental group received acupressure also receive routine care center. In the experimental group, Chinese acupressure on the ST36 (in the anterior part of the leg and within the width of a finger spines anterior tibia), SP6 (the medial tibia posterior side of the leg above the medial malleolus), GB34 (in the inferior frontal troughs the fibula bone), LU1 (in the chest outside the chest and in the intercostal space), KI1 (in the soles of the feet are 3/1 and 3/2 imaginary line between the second and third toes and heel) in sides for 2 minutes per point (1 minute direct pressure with the thumb until the person feels pain, distention, and more with the same amount of flow and pressure 1 minute massage is done in a clockwise direction) total 20-minute massage per person, 3 days per week for 8 weeks on patients there.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Fatigue. Timepoint: Before the study, 4 and 8 weeks after the start of the study. Method of measurement: پرسشنامه fss.</prim_outcome>
      <prim_outcome>Quality of life. Timepoint: Before the study, 4 and 8 weeks after the start of the study. Method of measurement: Sf36 questionnaire.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Second-hand smoke. Timepoint: Before the intervention. Method of measurement: Questions demographic questionnaire.</sec_outcome>
      <sec_outcome>Type tobacco And duration of use. Timepoint: Before the intervention. Method of measurement: Questions demographic questionnaire.</sec_outcome>
      <sec_outcome>Time to quit smoking. Timepoint: Before the intervention. Method of measurement: Questions demographic questionnaire.</sec_outcome>
      <sec_outcome>Number of cigarettes smoked per day. Timepoint: Before the intervention. Method of measurement: Questions demographic questionnaire.</sec_outcome>
      <sec_outcome>Smoking habits. Timepoint: Before the intervention. Method of measurement: Questions demographic questionnaire.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Research Center School of Nursing and Midwifery, Tehran</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2015-03-04</approval_date>
        <contact_name>Research Deputy Tehran University of Medical Sciences</contact_name>
        <contact_address>sixth floor of the University Center, Qods St, Keshavarz Blvd. Tel: 88987382 - Fax: 88989664 tehran  Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
