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IRCT138808271141N7 IRCT 2010-01-04 Royan Institute The efficacy of Cabergoline in preventing ovarian hyper stimulation in ART program The efficacy of Cabergoline in preventing ovarian hyper stimulation in ART program 2009-08-23 anticipated 130 Complete https://irct.ir/trial/202 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 3 ovarian hyperstimulation syndrome. Intervention 1: Gabergoline tablet (0.5 mg) daily until 6 days after oocytes retrieval. Intervention 2: Human albumin 20% infusion.
public Arezoo Arabipour
Royan Institute, Number 12, East Hafez Avenue, Bani Hashem Street, Resalat high way, Tehran, Iran
Tehran Iran (Islamic Republic of) 19395-4644 +98 21 2356 2307 arezoo.arabipoor@gmail.com Royan institute scientific Ensieh Tehraninejad MD
Royan Institute, Number 12, East Hafez Avenue, Bani Hashem Street, Resalat high way, Tehran, Iran
Tehran Iran (Islamic Republic of) 19395-4644 +98 212362307 Tehraninejad@royaninstitute.org Royan Institute Iran (Islamic Republic of) Inclusion Criteria: risk of developing OHSS, defined by the development of 20–30 follicles larger than 12 mm in diameter and retrieval of more than 20 oocytes, ovarian stimulation with long protocol Exclusion Criteria: Coasting cases, age more than 37 years, previous pelvic surgery, Intramural or submucosal myoma sizes > 5 CM, uterine polyps, Smoking, or alcohol addiction 15 years 37 years Female O94, O99 Other obstetric conditions, not elsewhere classified Treatment - Drugs Treatment - Drugs Gabergoline tablet (0.5 mg) daily until 6 days after oocytes retrieval Human albumin 20% infusion OHSS occurrence rate and severity of OHSS in two groups. Timepoint: 6 days after embryos transfer(ET). Method of measurement: accordance with the Golan 5 grade system. Pregnancy and early miscarriage rates. Timepoint: 5 week after embryo transfer until 12 gestational weeks. Method of measurement: Sonography. Royan Institute Approved 2009-07-28 Royan institute Royan Institute, Number 12, East Hafez Avenue, Bani Hashem Street, Resalat high way, Tehran, Iran Tehran Iran (Islamic Republic of)