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IRCT2015090823942N1 IRCT 2016-03-22 Vice-chancellor for Research of Zahedan University of Medical Sciences Total serum magnesium in the icteric neonates before and after phototherapy - Evaluation of total serum magnesium concentrations in neonatal hyperbilirubinemia before and after phototherapy 2010-04-04 anticipated 90 Complete https://irct.ir/trial/20326 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Screening, Other design features: To investigate total plasma levels of magnesium (tMg) in neonatal hyperbilirubinemia; before and after phototherapy serum bilirubin and plasma tMg will be measured in 90 otherwise-healthy term newborns with nonhemolytic hyperbilirubinemia. 4 Neonatal jaundice. Intervention group: The breast-fed newborns with exaggerated Bilirubin levels and those for whom initial managements could not decline increasing Bilirubin loads, phototherapy was employed based on the neonates’ age and Bilirubin levels.Forty-eight hours after phototherapy, the same measurement for tMg and total Serum Bilirubin was performed..
public Mehdi Shiri
Razi Hospital,Vahdat_e_eslami st.
Tehran Iran (Islamic Republic of) 1199663911 +98 21 5560 9951 msh.iums@gmail.com Razi hospital, Department of Dermatology, Tehran University of Medical Sciences scientific Mahmood Rezaee-pour
HESABI SQ.
Zahedan Iran (Islamic Republic of) +98 54 3341 6703 m.rezaypoor48@yahoo.com Department of Pediatrics, Zahedan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criteria: 90 otherwise-healthy term newborns with nonhemolytic hyperbilirubinemia during the first 4 weeks of life according to their age and standard graphs Exclusion criteria:Those neonates with anemia(Hb<8 ); symptoms in favor of hemolysis (ABO or Rh mismatch, G6PD deficiency, positive direct coombs test); history of Mg sulfate administration in mother and symptoms/signs in favor of infections; metabolic and endocrine disorders 1 day 15 days Both P59.9 Physiological jaundice (intense)(prolonged) NOS Treatment - Other Intervention group: The breast-fed newborns with exaggerated Bilirubin levels and those for whom initial managements could not decline increasing Bilirubin loads, phototherapy was employed based on the neonates’ age and Bilirubin levels.Forty-eight hours after phototherapy, the same measurement for tMg and total Serum Bilirubin was performed. Total serum bilirubin. Timepoint: Before and after phototherapy. Method of measurement: Spectrophotometry. Total serum magnesium. Timepoint: Before and after phototherapy. Method of measurement: Atomic absorption. - - Vice-chancellor for Research of Zahedan University of Medical Sciences Approved 2010-10-20 Ethics committee with supervision of Vice-chancellor for Research of Zahedan University of Medical S Hesabi sq. Zahedan Iran (Islamic Republic of)