IRCT20150928024236N5 IRCT 2018-10-07 Yazd University of Medical Sciences Effects of Melatonin on the incidence of Delirium The effect of Melatonin on the incidence of Delirium in hospitalized patients in the Intensive Care Unit 2016-07-22 anticipated 140 Complete https://irct.ir/trial/20509 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The random number generator was used in our study to assign each patient randomly in intervention or control group, Blinding description: The random number generator was used in our study to assign each patient randomly in intervention or control group (Randomized clinical trial). The random numbers were given by a study coordinator, who also encodes the drugs with matching random numbers. In addition, we formulated placebo with the same appearance to Melatonin tablet. Therefore, neither the patients nor the researchers evaluating the study outcome knew which patient is receiving Melatonin or placebo, until the study is over and the random code was revealed. 3 Delirium. Intervention 1: Intervention : Melatonin (Nature Made), tablet 3 mg, once daily (21:00 AM), orally for 7 consecutive days. Intervention 2: Control group: Placebo (consists of tricalcium phosphate, magnesium stearate and starch glue which is made in pharmacy faculty of Shahid Sadoughi University of Medical Sciences), once daily (at 21:00 AM), orally, for 7 consecutive days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.