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IRCT2015100724405N1 IRCT 2016-03-23 Dental Research Center The effect of autologous leukocyte platelet rich fibrin (LPRF) on the rate of orthodontic tooth movement- a prospective randomized clinical trial rate of orthodontic tooth movement following LPRF The effect of autologous leukocyte platelet rich fibrin (LPRF) on the rate of orthodontic tooth movement- a prospective randomized clinical trial 2015-03-20 anticipated 8 Complete https://irct.ir/trial/20620 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A orthodontic tooth movement. Intervention 1: in this study, after leveling in each quadrant of upper and lower arches, the extracted sockets would recieve LPRF in case group. Intervention 2: In control group, no LPRF would be applied in empty extracted sockets.
public Dr Azita Tehranchi
Daneshjoo Blv, Evin, Chamran Highway
Tehran Iran (Islamic Republic of) +98 21 2242 7752 azitatehranchi@yahoo.com Dental Research Center, Research Institute of Dental Sciences scientific Azita Tehranchi
Daneshjoo Blv, Evin, Chamran Highway.
Tehran Iran (Islamic Republic of) +98 21 2242 7752 azitatehranchi@yahoo.com Dental Research Center, Iran (Islamic Republic of) Inclusion Criteria: more than12 years old patients; bilaterally symmetric extraction of premolar teeth; no medicines or systemic illness; full banding/bonding of teeth in both arches. Exclusion Criteria: pregnancy; non-extraction treatment; syndromic &systemic illness or medication like NSAIDS that interfere with OTM; prior orthodontic treatment. 12 years 25 years Both Z51.8 Other specified medical care Other N/A in this study, after leveling in each quadrant of upper and lower arches, the extracted sockets would recieve LPRF in case group. In control group, no LPRF would be applied in empty extracted sockets. The amount of tooth movementand to compare the amount of tooth movement between maxillary and mandibular arches. Timepoint: [Time Frame: 0 days, 15 days, 1st month, 1.5 and 2nd month, 2.5 and 3rd month after start of treatment and conventional orthodontic]. Method of measurement: The amounts of OTM will be measured by comparing the changes of distance between the adjacent teeth in two weeks interval for three months. The exact amounts of tooth movement will be measured clinically by Boley Gauge Caliper with sharp tips located at the CEJ of crowns of the casts and then will be compared and double checked by another independent blind examiner ( to evaluate the interobserver and intraobserver reliability). Mucogingival defects, gingival recession, clinical attachement loss, probing depth, width of keratinized gingiva. Timepoint: Time Frame: 0 days, 15 Days, 1st month, 1.5 month. Method of measurement: aesculap periodontal probe. Dental Research Center Approved 2014-03-02 ETHICAL COMMITTEE,RESEARCH INSTITUTE OF DENTA SCIENCESL EVIN DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY IF MEDICAL SCIENCSES Tehran Iran (Islamic Republic of)