]>
IRCT2017102325267N5 IRCT 2017-11-13 Vice chancellor for research, Tehran University of Medical Sciences Comparison between two different diets in children and adolescents with cystic fibrosis The comparison between high calorie, high fat diets with different glycemic indexes effect on some biomarkers related to diabetes and inflammatory factors and cytokines in children and adolecents with cystic fibrosis. 2017-11-22 anticipated 42 Complete https://irct.ir/trial/21158 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 2 cystic fibrosis. Intervention 1: Intervention group: following high fat, high calorie diet with low gycemic index for three months. Intervention 2: control group: following high fat, high calorie diet, with gycemic index higher than 55 for three months.
public Maryam Mahmoudi
School of Nutritional Sciences & Dietetics, Tehran University of Medical Sciences, No: 44 Hojjat-dost Alley, Naderi St., Keshavarz Blvd, Tehran, Iran
Tehran Iran (Islamic Republic of) +98 21 8895 5698 mahmoodi_maryam@yahoo.com Tehran University of Medical Sciences scientific Maryam Mahmoudi
School of Nutritional Sciences & Dietetics, Tehran University of Medical Sciences, No: 44 Hojjat-dost Alley, Naderi St., Keshavarz Blvd, Tehran, Iran
Iran (Islamic Republic of) +98 21 8895 5698 mahmoodi_maryam@yahoo.com Tehran University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: children and adolescents aged 2-18; children and adolescents who affected disease is confirmed by genetic or sweat test; willingness to cooperate Exclusion criteria: unwilling to cooperate and continue; inability to pursue each types of the diet; urgent need of hospitalization during trial; urgent need of operation during trial 2 years 19 years Both E84 cystic fibrosis Prevention Prevention Intervention group: following high fat, high calorie diet with low gycemic index for three months control group: following high fat, high calorie diet, with gycemic index higher than 55 for three months Fasting blood glucose. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. HDL cholostrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically. LDL cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically. Total cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically. HbA1c. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. INF gamma. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. IL17-A. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. IL-10. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. IL-6. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit. Height. Timepoint: begining of the trial and three months. Method of measurement: meter. Weight. Timepoint: begining of the trial and three months. Method of measurement: Scale. Vice chancellor for research, Tehran University of Medical Sciences Approved 2017-08-14 Ethical Committee of Tehran University of Medical Sciences Central building of Tehran University of Medical Sciences, conjunction of Keshavarz Blvd and Qods Street, Tehran, Iran Tehran Iran (Islamic Republic of)