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IRCT2015122825729N1 IRCT 2016-07-30 personal fund Drug effect on tooth sensitivity after bleaching Effect of systemic capsaicin on the prevention of tooth sensitivity after in-office bleaching 2016-06-21 anticipated 60 Complete https://irct.ir/trial/21476 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 0 (exploratory trials) tooth discolaration. Intervention 1: (Control group:placebo,taking similar to intervention group, every 8 hours (three times a day). Intervention 2: Intervention group:Capsaicin,capsule 0/25%(50 mg),oral,take every 8 hours (three times a day).( capsules made in Isfahan pharmacology school and capsaicin powder is taken from Amin Pharmaceutical Company.
public Maryam Montazeri Shahtouri
Hear jerib St, Isfahan University of Medical Sciences
Isfahan Iran (Islamic Republic of) +98 316692588 maryammontazeri.sh@gmail.com Isfahan Dental School scientific pouran samimi dehkordi
Hezar jerib St, Isfahan university of medical sciences
Isfahan Iran (Islamic Republic of) +98 316692588 samimi@dnt.mui.ac.ir school of dentistry Iran (Islamic Republic of) Inclusion criteria: 1) at least 18 yrs old 2) good oral hygiene 3) 6 anterior maxillary teeth without restorations on labial surface 4) exist all 6 anterior maxillary teeth 5) no smoking 6) no recession 7) central incisor with A3 or lighter according (Vita shade guide,Vita Zahnfabrik ,Bad Sackingen,Germany) Exclusion criteria : 1) who have a history of nay medical diseases that may interfere with the study 2)smoking in the past 30 days 3) have oral lesion 4) pregnant or lactating women 5) calculus or sever tooth discoloration 6) tooth sensitivity 7) expose dentine into oral cavity 8) who use desensitizer products 9) having sever tooth sensitivity after bleaching no limit no limit Both K03.6 staining,tooth,teeth (hard tissues) (extrinsic Placebo Treatment - Drugs (Control group:placebo,taking similar to intervention group, every 8 hours (three times a day). Intervention group:Capsaicin,capsule 0/25%(50 mg),oral,take every 8 hours (three times a day).( capsules made in Isfahan pharmacology school and capsaicin powder is taken from Amin Pharmaceutical Company Tooth sensitivity. Timepoint: 1 h before operation and taking capsules,just after operation,1h and 24h after operation. Method of measurement: VAS form. personal fund Approved 2016-06-06 Research chancellery of Isfahan university of medical sciences Hezar jerib St, Isfahan university of medical sciences Isfahan Iran (Islamic Republic of)