IRCT2016021125732N2 IRCT 2016-05-01 Vice Chancellor for Research, Semnan University of Medical sciences Clinical and laboratory Efects of vitamin D supplementation in adolescent with polycystic ovarian syndrome and vitamin D deficiency Clinical and laboratory Efects of vitamin D supplementation in adolescent with polycystic ovarian syndrome and vitamin D deficiency 2016-01-21 anticipated 50 Complete https://irct.ir/trial/21479 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 Adolescent with polycystic ovarian syndrome and vitamin D deficiency. Intervention 1: In the intervention group, 50 000 IU of vitamin D weekly for 8 weeks will be given. PCOS symptoms, patients should not interfere with effective drugs such as oral contraceptives COCS, metformin, medroxyprogesterone and so on. The only injectable progesterone injections in case of amenorrhea has 45 days from the previous cycle dose of 200 mg intramuscularly for induction menstruation is used. Intervention 2: The control group, placebo will be given for 8 weeks. PCOS symptoms, patients should not interfere with effective drugs such as oral contraceptives COCS, metformin, medroxyprogesterone and so on. The only injectable progesterone injections in case of amenorrhea has 45 days from the previous cycle dose of 200 mg intramuscularly for induction menstruation is used.