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IRCT2016011125957N1 IRCT 2016-02-07 Oil Version Factory The effect of flaxseed oil in the treatment of non-alcoholic fatty liver Compare the effect of flaxseed and sunflower oil on anthropometric characteristics, pressure and blood lipids and liver enzymes in patients with nonalcoholic fatty liver in overweight patients with a low-calorie diet 2015-12-16 anticipated 80 Complete https://irct.ir/trial/21643 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Nonalcoholic Fatty Liver. Intervention 1: The control group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive sunflower oil. Diet and recommendations are presented separately for each person. The exact consumption of oil is measured by graded modules. Outcomes measured before and after the intervention. At the beginning and end of study and end of each month, 3-day recall, blood pressure and anthropometric indices will be taken. Intervention 2: The intervention group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive flaxseed oil. Diet and recommendations are presented separately for each person. The exact consumption of oil is measured by graded modules. Outcomes measured before and after the intervention. At the beginning and end of study and end of each month, 3-day recall, blood pressure and anthropometric indices will be taken.
public Doctor Masume Akhlaghi
Shiraz, Iran, Razi School of Nutrition and Food Science
Shiraz Iran (Islamic Republic of) +98 71372510018 shahlarezaei13932014@gmail.com Department of Food Science and Nutrition scientific Doctor Masume Akhlaghi
Shiraz, Razi Blvd.
Shiraz Iran (Islamic Republic of) +7 1372510018 shahlarezaei13932014@gmail.com Department of Nutrition and Food Science Iran (Islamic Republic of) Inclusion criteria: having NAFLD by medical diagnosis (using ultrasound) ; BMI = 25 and above ; willingness to participate in the study, the absence of diabetes mellitus type 2 ;heart disease ;cardiovascular and liver disease (cirrhosis, liver disease Alcohol, viral hepatitis, autoimmune hepatitis, primary biliary cirrhosis, biliary obstruction, liver damage induced by drugs hereditary Hemochromatosis, sclerosis cholangitis and antitrypsin deficiency of α-a-1) ;other serious diseases such as cancer ;kidney failure and celiac disease, etc) ;lack of pregnancy ;lactation ;lack of drugs that are causing fatty liver (methotrexate, tamoxifen, Valproate, etc.) ;avoiding the use of any type of lipid lowering agents (atorvastatin, lovastatin, pravastatin, etc.) ;fibrates (gemfibrozil, fenofibrate) ;lack of malnutrition ;have no special diets such as vegan and vegetarian ;not drinking alcohol and having over 18 years of age. Exclusion criteria: non-compliance with recommended diet for more than 15 days over 3 months ;acute or infectious disease ;hospitalization or in cases where the criteria mentioned is. no limit no limit Both K76.0 (Nonalcoholic fatty liver disease (NAFLD Treatment - Drugs Treatment - Other The control group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive sunflower oil. Diet and recommendations are presented separately for each person. The exact consumption of oil is measured by graded modules. Outcomes measured before and after the intervention. At the beginning and end of study and end of each month, 3-day recall, blood pressure and anthropometric indices will be taken. The intervention group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive flaxseed oil. Diet and recommendations are presented separately for each person. The exact consumption of oil is measured by graded modules. Outcomes measured before and after the intervention. At the beginning and end of study and end of each month, 3-day recall, blood pressure and anthropometric indices will be taken. Blood pressure. Timepoint: Before the intervention, after the intervention and the end of each month. Method of measurement: Barometer. Lipid profile. Timepoint: Before the intervention, after intervention. Method of measurement: blood test. Anthropometric indices. Timepoint: Before the intervention, after the intervention and the end of each month. Method of measurement: Devices BIA, scales, meters. Liver enzymes. Timepoint: Before the intervention, after intervention. Method of measurement: blood test. Changing in the degree of fatty liver. Timepoint: Before the intervention, after the intervention. Method of measurement: Ultrasound. Oil Version Factory Approved 2015-12-13 Shiraz University of Medical Sciences, School of Nutrition Shiraz, Razi Blvd. Shiraz Iran (Islamic Republic of)