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IRCT2016012826244N1 IRCT 2016-07-19 Vice Chancellor Of Research Mashhad University of Medical Sciences The comparison of honey vaginal gel with metronidazole vaginal gel on treatment of recurrent bacterial vaginosis The Comparison effects of honey vaginal gel and vaginal gel metronidazole on treatment of recurrent bacterial vaginosis 2015-11-22 anticipated 61 Complete https://irct.ir/trial/21791 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Recurrent bacterial vaginosis. Intervention 1: Intervention1: Metronidazole vaginal gel in this study, 750 mg (0.75 percent) to 0.75 grams per 100 grams of metronidazole to using an applicator is recommended every night (about 5cc) before bed for 7 night. Intervention 2: Intervention 2: produced honey gel with the Iranian standards and license-mahram 30/10233.represent every night an applicator (about 5cc) applied at night before bed for seven night.
public Negar Saki
Doktora intersection, Ibn Sina Street, Mashhad
Mashhad Iran (Islamic Republic of) +98 51 3859 1511 sakin911@gmail.com Mashhad University of Medical Sciences scientific Mahin Tafazoli
Doktora intersection, Ibn Sina Street, Mashhad
Mashhad Iran (Islamic Republic of) 00 tafazolim@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: proven recurrent bacterial vaginosis based on the history (of 3 or more than 3 times recurrence of symptoms and the clinical Amsel criteria; women 18-49 years old; married; single spouse; the absence of pregnancy and lactation; signed informed consent to participate in the study; not taking any vaginal medications in last 48 hours; not taking any antibiotics during the last 3 weeks; lack of vaginal intercourse or shower in the last 24 hours; no smoking; no alcohol consumption ; not taking any anticoagulants such as Coumadin and disulfiram; there is not any known medical condition like diabetes; blood Dyskrazy; thyroid disease and liver disease history; do not use IUD. Exclusion criteria: patient's request ; the medication is not used for more than once; no condom use during the course of treatment; Menstruation . no limit no limit Female N76.7 Other specified inflammation of vagina and vulva Treatment - Drugs Treatment - Drugs Intervention1: Metronidazole vaginal gel in this study, 750 mg (0.75 percent) to 0.75 grams per 100 grams of metronidazole to using an applicator is recommended every night (about 5cc) before bed for 7 night Intervention 2: produced honey gel with the Iranian standards and license-mahram 30/10233.represent every night an applicator (about 5cc) applied at night before bed for seven night Recurrent bacterial vaginosis. Timepoint: Before treatment and after treatment. Method of measurement: Observation. Recurrent bacterial vaginosis treatment. Timepoint: 7 and 30 days after treatment. Method of measurement: observation. Vice Chancellor Of Research Mashhad University of Medical Sciences Approved 2015-11-08 Mashhad University of Medical Sciences Ethics Committee Doctora intersection, Ibn Sina Street, Mashhad Mashhad Iran (Islamic Republic of)