IRCT2016042127513N1 IRCT 2016-06-15 Vice chancellor for Research of Sabzevar University of Medical Sciences The effect of green tea extract on oral lesions The effect of green tea extract on oral lesions in intubated patients admitted in the ICU 2016-02-20 anticipated 50 Complete https://irct.ir/trial/22516 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Other design features: In this double blind randomized clinical trial samples in the two groups will be labeled by letters A, B. For randomization of the patients,random permutation of blocks was used. In this method ,there were four patients in each block(2 chlorhexidin and 2 green tea). Then blocks were chosen randomly and The researcher who measures the Implications of the study is unaware of the intervention groups. Patients are also blind as they are unconscious at the time of intervention. 2 Gingivitis. Intervention 1: Intervention group: After approving of the study by Ethics committee of Gonabad University of medical sciences and completing the written consent forms by all participants in the study, Patients are divided randomly into two equal groups: 25 patients in intervention and25 in control group. In the intervention group, chlorhexidine solution was used and after one hour10 % green tea extract was used. This action is done every 8 hours during 4 days. Intervention 2: Control group: control group members wash their mouth with 0.2 %( zero point two percent) chlorhexidine solution. This action is also done every 8 hours for 2 minutes during 4 days but for control group. Also, the observation of mouth is done by BOAS and MPS every 8 hours before utilizing a mouthwash (before washing mouth by chlorhexidine solution). Then, we record it in a checklist.