IRCT2016061228402N1 IRCT 2016-06-19 Vice chancellor for research of Ahvaz Jundishapur University of Medical Sciences Effects of laser therapy on diminishing pain after impacted lower third molar surgery Assessment the effects of low-level laser therapy after impacted lower third molar surgery 2015-03-21 anticipated 44 Complete https://irct.ir/trial/23050 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. 3 Impacted third molar surgery. Intervention 1: Intervention group: The patients in intervention group received low-level laser therapy using diode laser (G-laser 25, Galbiati, Italy) with continuous length wave of 980 nm with hand piece of 600 µm. The laser energy was justified on 300 mW and was emitted for 180 seconds (60 seconds for each site). The laser was administrated into two manners including intraoral at two points of vestibular and lingual at the distance of 1 cm from surgery site and extraorally at the conjunction of masseter muscle immediately after surgery and repeated at 24 hours after surgery as well. Intervention 2: Control group: patients received 1 gr amoxicillin orally per 12 hours up to 5 days and 1600 mg ibuprofen up to 2 days.