IRCT2016080228664N2 IRCT 2016-08-31 Vice chancellor for research and thecnology of Hamedan University of Medical Sciences The effect of wet cupping on regulation of vaginal bleeding in Pcos Poly Cystic Ovarian Syndrome Comparison of the efficacy of wet cupping and blood donation on decrease of menstruation period and insulin resistance in polycystic ovarian syndrome (PCOS) 2016-07-22 anticipated 60 Complete https://irct.ir/trial/23198 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Pcos. Calves wet-cupping will done at the 26th day of menstruation cycle in intervention group. When the patient is in the prone position, calf muscle is suctioned repeatedly to provide a negative pressure. Then under aseptic condition shallow incisions are made by a surgical blade parallel to the body plans and bleeding from incisions will be collected inside the cup through three times suctions. Then skin will be cleaned and covered by dressing. Vein bleeding will done in control group at 26th day from LMP. Intervention will done only once..