IRCT2016070728821N1 IRCT 2016-08-24 Vice chancellor for research, Shahid Beheshti University of Medical Sciences Efficacy of aspirin desensitization in nasal polyposis Clinical and biochemical Aspirin desensitization effectiveness assay in patients with nasal polyposis and aspirin sensitive asthma 2016-06-21 anticipated 34 Complete https://irct.ir/trial/23285 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Blocking. N/A nasal polyp. Intervention 1: Intervention group : Aspirin sensitive nasal polyposis patients will recieve 2 days desensitization protocol in case group, that will be done by Ketrolac nasal drop (1 and 2 drop in each canal with 30 minute interval) and after that 40 and 60 mg aspirin feeding in day one and 80,160 and 325 mg aspirin in day 2, all with 90 minute interval. After desensitization 650 mg aspirin per day start in first month. Intervention 2: Control group: Aspirin sensitive patients in control group receive starch tablet instead of aspirin.