IRCT2016080729234N1 IRCT 2017-06-06 Vice Chancellor for research of Sabzevar University of Medical Sciences Effect of mechanical ventilation on oxynation and hemodynamic in head trauma. The Effect Comparison of synchronized intermittent mandatory ventilation and airway pressure release ventilation in oxynation and hemodynamic parameters in patients with head trauma. 2016-08-22 anticipated 72 Complete https://irct.ir/trial/23553 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Supportive. N/A Head trauma. Intervention 1: Intervention of this research is a ventilation mode is called Airway Pressure Release Ventilation that will be applied through ventilator and tracheal tube for half an hour. This mode is an inverse ratio mode in which patient airway pressure is fluctuated between high pressure and low pressure. In this intervention, the duration of high pressure is 4.5 sec and duration of low pressure is 0.5 sec. The high-level pressure will be determined based on the patient's required tidal volume. The patients in group 1 will receive SIMV for two hours then ABG will be taken half an hour and two hours after changes. Then ventilator mode will be switched to APRV for two hours and ABG will be taken half an hour and two hours later. In all stages the values for ABG and vital signs will be recorded. Intervention 2: The patients in group 2 will receive APRV for two hours and after that ABG will be taken half an hour and two hours after changes. Then ventilator mode will be switched to SIMV for two hours and ABG will be taken half an hour and two hours later. In all stages the values for ABG and vital signs will be recorded.