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IRCT201103011155N11 IRCT 2011-07-03 Vince chancellor for reaserch guilan univercity of medical sciences Comparing regimens ( Bismuth sub-citrate , Omeprazole , Amoxicillin , Clarithromycin , Tinidazole ) and ( Bismuth sub citrate , Omeprazole , Tetracycline , Metronidazole , Ofloxacin ) on the eradication rate of Helicobacter pylori infection in non responder dyspeptic patients Comparing the five-drug regimen ( Bismuth sub-citrate , Omeprazole , Amoxicillin , Clarithromycin , Tinidazole ) and ( Bismuth sub citrate , Omeprazole , Tetracycline , Metronidazole , Ofloxacin ) on the eradication rate of Helicobacter pylori infection in non responder dyspeptic patients 2011-02-09 anticipated Complete https://irct.ir/trial/236 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 dyspepsia. Intervention 1: The first group treated with diet five drug protocol I ( Bismuth sub citrate 240 miligeram two time in day Construction Company Kimdaru drug 120 miligeram of two every 12 hours is given , Omeprazole 20 miligeram two time in day Construction Company doctor abidi capsule 20 miligeram every 12 hours of a number , Amoxicillin 1 geram two time in day Construction Co , two 500 mg capsules every 12 hours , Clarithromycin 500 miligeram two time in day Abbott Construction Company a number every 12 hours , making pars Tinidazole 500 miligeram two time in day drug every 12 hours that a number of drug to be prescribed for a week. Intervention 2: Another group treated with protocol II (Bismuth sub citrate 240 miligeram two time in day Construction Co Kimydaru one number per 12 hours , Omeprazole 20 miligeram two time in day Construction Company doctor abidi a number every 12 hours , Tetracycline 500 miligeram two time in day Construction Company Razak two every 12 hours , Metronidazole 500 miligeram two time in day Construction Company Alborz number every 12 hours , Ofloxacin 200 miligeram two time in day Construction Co. exir number every 12 hours a week will be given.
public Farahnaz Joukar
Sardar Jangal Ave, Gastrointestinal and Liver Diseases Research Center, Razi hospital, Rasht
Rasht Iran (Islamic Republic of) 955655-41448 +98 13 1553 5116 info@gldrc.org Gastrointestinal and Liver Diseases Research Center scientific Dr.Fariborz Mansour-Ghanei
Sardar Jangal Ave, Gastrointestinal and Liver Diseases Research Center, Razi Hospital, Rasht, Iran
Rasht Iran (Islamic Republic of) 95655-41448 +98 13 1553 5116 info@gldrc.org Gastrointestinal and Liver Diseases Research Center Iran (Islamic Republic of) Inclusion: In this study , helicobacter pylori positive patients over 15 years and less than 65 years that under drug treatment regiment quadriple or triple placed urea breath test (UBT) using carbon 14 (C14 or C13 or stoolAg) with the European protocol again have been positive , will enter the study. Exclusion : Pregnant women , Patients with gastric malignancy , Cirrhosis , Patients with allergy to Amoxicillin or Clarithromycin , Omeprazole , Tetracycline , Ofloxacin , Metronidazole and Tinidazole , Colestramin Consumption , Renal failure , History of seizures , Blood disorders , Fauvism and treatment of patients with incomplete (less than 80%) will be excluded. 15 years 65 years Both k30 Dyspepsia Treatment - Drugs Treatment - Drugs The first group treated with diet five drug protocol I ( Bismuth sub citrate 240 miligeram two time in day Construction Company Kimdaru drug 120 miligeram of two every 12 hours is given , Omeprazole 20 miligeram two time in day Construction Company doctor abidi capsule 20 miligeram every 12 hours of a number , Amoxicillin 1 geram two time in day Construction Co , two 500 mg capsules every 12 hours , Clarithromycin 500 miligeram two time in day Abbott Construction Company a number every 12 hours , making pars Tinidazole 500 miligeram two time in day drug every 12 hours that a number of drug to be prescribed for a week. Another group treated with protocol II (Bismuth sub citrate 240 miligeram two time in day Construction Co Kimydaru one number per 12 hours , Omeprazole 20 miligeram two time in day Construction Company doctor abidi a number every 12 hours , Tetracycline 500 miligeram two time in day Construction Company Razak two every 12 hours , Metronidazole 500 miligeram two time in day Construction Company Alborz number every 12 hours , Ofloxacin 200 miligeram two time in day Construction Co. exir number every 12 hours a week will be given. Helicobacter pylori eradication. Timepoint: 12 week. Method of measurement: ureas breath test with c14 and stool antigen. Vince chancellor for reaserch guilan univercity of medical sciences Approved 2011-03-03 Guilan University of Medical Sciences. Ethics Committee Gastrointestinal and Liver Diseases Research Sardar Jangal Ave, Gastrointestinal and Liver Diseases Research Center, Razi Hospital, Rasht, Iran Rasht Iran (Islamic Republic of)