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IRCT138905172602N4 IRCT 2011-08-05 Tehran University of Medical Sciences Effect of Q10 on multiple sclerosis patients Effect of coenzyme Q10 on inflammatory factors in multiple sclerosis patients. 2011-09-21 anticipated 50 Complete https://irct.ir/trial/2375 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. 3 multiple sclerosis. Intervention 1: Intervention group: Q10 supplement (500mg/day) for 90 days. Intervention 2: Control group: 2 capsules/day including dietary fiber.
public Dr Shahriar Eghtesadi
School of Health, Alvand Ave, Arjanteen Square
Tehran Iran (Islamic Republic of) +98 21 8877 9118 egtesadi@iums.ac.ir, eghtesadi@yahoo.com School of Health, tehran University of Medical Sciences scientific Dr. Shahriar Eghtesadi
School of Health, Alvand Ave, Arjanteen Square
Tehran Iran (Islamic Republic of) +98 21 8877 9118 egtesadi@iums.ac.ir, egtesadi@yahoo.com School of Health, tehran University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: age 18-51 years, able to provide informed consent and diagnosed with relapsing remitting MS. Exclusion criteria: MS exacerbation during the study, systemically administered corticosteroids during the study , pregnant or breast-feeding , other significant health problem (e.g. active coronary heart disease, liver disease, pulmonary disease, diabetes mellitus and other autoimmune disease) that might increase the risk of subject experiencing adverse events. Consumption of vitamin, mineral and antioxidant supplement 30 days before study entry, Any condition which would make the subject, in the opinion of the investigator, unsuitable for the study and compliance less than 70%. 18 years 51 years Both G35 Multiple sclerosis Treatment - Drugs Placebo Intervention group: Q10 supplement (500mg/day) for 90 days Control group: 2 capsules/day including dietary fiber TGF-B. Timepoint: 12 weeks after the intervention. Method of measurement: ELISA. Serum TNF-a concentration. Timepoint: 12 weeks after the intervention. Method of measurement: labratory kit. IL-4. Timepoint: 12 weeks after the intervention. Method of measurement: ELYSA. IL-6. Timepoint: 12 weeks after the intervention. Method of measurement: ELISA. MMP-9. Timepoint: 12 weeks after the intervention. Method of measurement: ELISA. Tehran University of Medical Sciences Approved 2011-05-10 School of Health, Tehran University of Medical Sciences Alvand Ave, Arjanteen Square Tehran Iran (Islamic Republic of)