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IRCT2016092129895N1 IRCT 2016-10-13 Ardabil University of Medical Sciences The effect of glutamine supplementation on serum levels of Adiponectine and TNFα after exhaustive exercise in young males The effect of glutamine supplementation on serum levels of Adiponectine and TNFα after exhaustive exercise in young males 2016-04-20 anticipated 30 Complete https://irct.ir/trial/23914 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 2-3 Young healthy males. Intervention 1: Given 0.3 gr Glutamine in per Kgr weight of body with 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for intervention group. Intervention 2: Given 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for control group.
public Leila Mollazadeh
Biochemistry Dept, Ardabil University of Medical Sciences, Ardabil University of Medical Sciences, Daneshgah Avenue, Ardabil, Iran.
Ardabil Iran (Islamic Republic of) 5155653466 +98 45 1383 1568 le.mollazadeh@arums.ac.ir Ardabil University of Medical Sciences scientific Ali Nemati
Nutritional Biochemistry Dept., Faculty of Medicine, Ardabil University of Medical Sciences, Daneshg
Ardabil Iran (Islamic Republic of) 5618953141 +98 45 1551 2788 ali.nemati@arums.ac.ir Ardabil University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Young healthy males with moderate physical activity in 18-30 years old. Exclusion criteria: Individuals with any diseases; smoking; alcoholism and other supplements consumption; having certain dietary; professional training; sedentary and having BMI over 25 and less than18.5 kg.m2 18 years 30 years Male Z02.5 Examination for participation in sport Other Placebo Given 0.3 gr Glutamine in per Kgr weight of body with 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for intervention group Given 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for control group Exhaustive exercise time. Timepoint: At the end of exercise. Method of measurement: With signs and symptoms of exhaustion. Total cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry. Triglyceride. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry. HDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry. HsCRP. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Adiponectin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Height. Timepoint: At the beginning of intervention. Method of measurement: Stadiometers. Malondialdehyde. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Weight. Timepoint: At the beginning of intervention. Method of measurement: Digital scales. Total antioxidant capacity. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Tumor necrosis factor-alpha. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. LDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry. Matrix metalloproteinase-2. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Matrix metalloproteinase-9. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Interlukine-6. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Leptin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Oxidated LDL. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA. Ardabil University of Medical Sciences Approved 2016-02-09 Ethic Committee of Ardabil University of Medical Sciences Ethic Committee of Ardabil University of Medical Sciences, Vice Chancellor for Research, Ardabil University of Medical Sciences, Ardabil University of Medical Sciences, Daneshgah Avenue, Ardabil, Iran Ardabil Iran (Islamic Republic of)