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IRCT2016092229914N1 IRCT 2017-05-01 Vice CHancellor For Research, Iran university Of Medical Sciences Ultrafiltration effect on coronary artery bypass surgery Zero-balance ultrafiltration method to evaluate the effect on clinical outcomes in patients undergoing coronary artery bypass surgery 2016-11-21 anticipated 75 Complete https://irct.ir/trial/23926 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 Coronary Artery Disease. Intervention 1: Hemofilter action in the intervention group since the beginning of cardiopulmonary bypass connected to the system and maintain the volume of the tank by adding intravenous normal saline or ringer on the basis of clinical status, His blood will be filtered. Intervention 2: In the control group there is.
public Robabeh KHalili
School of Nursing, Valiasr street, Tehran
Tehran Iran (Islamic Republic of) +98 88882885 robabekhalili64@gmail.com Iran University of Medical Sciences scientific TaherehNajafi GHezelgeh
School of Nursing, Vali Asr Street, Tehran
Tehran Iran (Islamic Republic of) +98 88882885 taherepaniz@yahoo.com Iran University of Medical Sciences Iran (Islamic Republic of) Non-inclusion criteria Liver failure as ((AST> 40 unit / L) and (ALT> 40 unit / L);A history of heart surgery;High serum creatinine1/5mg / dL; And patients who received the drug because before during 5 days acute renal failure have had severe narrowing of the carotid both carotid or one of them; Surgery emergency; IE; Ejection fraction of the left ventricle less than 30 percent of patients with Severe failure right ventricle Hemoglobin less than 10;Mass index BMI greater than 40;Benign and malignant cancers;Clamped aortic bypass for more than 120 minutes and 150 minutes; Pulmonary function test abnormal preoperative FEV1 <65 Exclusion criteria Prime 8/5000 Autologus do the opposite; Using the CUF; Using MUF; Patient died during surgery; Use of Intraoperative balloon pump;Use of ECMO; The need to stay open sternum after surgery; The patient needs cardiopulmonary resuscitation no limit no limit Both I25.0 Atherosclerotic cardiovascular disease, so described Treatment - Other N/A Hemofilter action in the intervention group since the beginning of cardiopulmonary bypass connected to the system and maintain the volume of the tank by adding intravenous normal saline or ringer on the basis of clinical status, His blood will be filtered In the control group there is Cerebral oxygenation. Timepoint: 1.Preoperative2.Start operation3.Intraoperative4.Postoperative2. Method of measurement: Invos devices. Arterial blood gases. Timepoint: Before surgery2.Start operation3.Intraoperative4.End the practice of5.6 hours after surgery. Method of measurement: Arterial blood gas measurement. Liver enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory. Kidney enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory. Cardiac arrhythmia. Timepoint: Preoperative and postoperative. Method of measurement: ECG machine. Vice CHancellor For Research, Iran university Of Medical Sciences Approved 2017-01-07 Ethics Committee of the University of Medical Sciences Hemmat Tehran Tehran Iran (Islamic Republic of)