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IRCT2016111530905N1 IRCT 2017-03-01 Imam Hossein Hospital PTX and Contrast Induced Nephropathy ¬¬A randomized double blind placebo controlled trial examining the effects of Pentoxifylline on Contrast Induced Nephropathy reduction after percutaneous coronary intervention in high risk candidates 2014-01-01 anticipated 110 Complete https://irct.ir/trial/24422 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. 3 patients candidate for percutaneous coronary intervention. Intervention 1: placebo capsules plus N-acetyl cysteine. Intervention 2: Pentoxifylline plus N-acetyl cysteine.
public Dr.Farnaz Barzi
Shahid Madani st
Tehran Iran (Islamic Republic of) +98 21 73430 farnazbarzi@sbmu.tums.ac.ir School of Medicine, ShahidBeheshti University of Medical Sciences scientific Dr.Farnaz Barzi
Shahid Madani
Tehran Iran (Islamic Republic of) +98 21 73430 farnazbarzi@sbmu.tums.ac.ir School of Medicine, ShahidBeheshti University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criterion was only Mehran score more than or equal to 11. Exclusion criteria included need for urgent coronary angiography in the first 48 hours after admission, history of contrast media usage in previous 14 days or renal failure in recent six months, multiple myeloma, pregnancy or breastfeeding and pre-planned use of any other measure for CIN prevention apart from PTX consumption. no limit no limit Both N14.1 نفروپاتی القا شده بوسیله سایر داروها، مواد بیولوژی و دارویی Treatment - Drugs Treatment - Drugs placebo capsules plus N-acetyl cysteine Pentoxifylline plus N-acetyl cysteine Contrast Induced Nephropathy. Timepoint: once. Method of measurement: 48 hours after angiography. Cratinine. Timepoint: before and 48 hours after the intervention. Method of measurement: Laboratory unit. Imam Hossein Hospital Approved 2012-11-11 Ethical Committee of the ShahidBeheshtiUniversity of Medical Sciences ShahidBeheshtiUniversity of Medical Sciences Tehran Iran (Islamic Republic of)