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IRCT2016120431226N1 IRCT 2017-01-18 Vice Chancellor for research of Ahwaz University of Medical Science Effect of ischemia in cardio surgery patients Studing the effect of remote ischemic preconditioning on blood Troponin I level in patients undergoing open cardiosurgery 2016-12-21 anticipated 28 Complete https://irct.ir/trial/24610 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 coronary disease/valvular disease. Intervention 1: Intervention group: after induction of anesthesia and intubating the patient under open cardiac surgery, pneumatic cuff will be fastened on patient’s arm and will be inflated up to 200 mmHg and kept in this condition for 5 minutes and then deflated and the arm will rest for 5 minutes .This procedure will be repeated two times more. Intervention 2: Control group: The pneumatic torniquet cuff will only be fastened and will not be inflated.
public Mohsen Moaddeli
Golestan hospital, Farvadin St, Golestan Blv
Ahwaz Iran (Islamic Republic of) 61357-15794 +98 61 3336 7543 moaddeli.m@ajums.ac.ir; moadelimohsen@yahoo.com Ahwaz University of Medical Science scientific Mohsen Moaddeli
Golestan hospital, Farvardin St, Golestan Blv
Ahwaz Iran (Islamic Republic of) 61357-15794 +98 61 3336 7543 moaddeli.m@ajums.ac.ir; moadelimohsen@yahoo.com Ahwaz University of Medical Science Iran (Islamic Republic of) Including criteria: ASA 2,3; normal troponin one level; no recent myocardial infarction; ejection fraction more than 35%; no renal and hepatic dysfunction; no arterio-venous fistula; no lymph edema. Excluding criteria: ASA 4 or more; elevated baseline troponin I; myocardial infarction in recent 4 weeks; ejection fraction less than 35%; renal dysfunction; arterio-venous fistula; lymph edema; severe endocrine or hepatic dysfunction. 19 years 69 years Both - - Treatment - Other Treatment - Other Intervention group: after induction of anesthesia and intubating the patient under open cardiac surgery, pneumatic cuff will be fastened on patient’s arm and will be inflated up to 200 mmHg and kept in this condition for 5 minutes and then deflated and the arm will rest for 5 minutes .This procedure will be repeated two times more. Control group: The pneumatic torniquet cuff will only be fastened and will not be inflated. Troponin I. Timepoint: time0, 6 and 24 hour after intervention. Method of measurement: quantitative troponin kit. Intubation time. Timepoint: 6 hour, 24 hour. Method of measurement: clock. Systolic and diastolic pressure. Timepoint: time 0,time 6,time 24. Method of measurement: Sphygmomanometer. Vice Chancellor for research of Ahwaz University of Medical Science Approved 2016-11-26 Ethics committee of Ahwaz University of Medical Science Golestan Blv, Ahwaz University of Medical Science Ahwaz Iran (Islamic Republic of)