]>
IRCT2017010131695N1 IRCT 2017-01-29 Vice chancellor for research, Kurdistan University of Medical Sciences The effect of vitamin D supplementation in the prevention of recurrence of preeclampsia in pregnant women with a history of preeclampsia The effect of vitamin D supplementation in the prevention of recurrence of preeclampsia in pregnant women with a history of preeclampsia 2017-01-09 anticipated 142 Complete https://irct.ir/trial/24879 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Other design features: In this study, then matching the inclusion and exclusion criteria and obtaining informed consent, pregnant women were assigned to intervention and control groups randomly,by using random number table.Study participants are unaware of assignment in to the intervention or control groups.Physician is not aware of each patient's group. 3 preeclampsia. Intervention 1: Intervention 1 : Administration of Vitamin D3, 50000 IU ,pearl. Intervention 2: intervention 2: Administration of placebo.
public Shole Shah Gheibi
Besat hospital, Keshavarz Blvd, Sanandaj
Sanandaj Iran (Islamic Republic of) 66196-67761 +98 87 3328 2001 shahgheibi@yahoo.com Besat Hospital, Sannandaj scientific Farnaz Zandvakili
Besat Hospital, Keshavarz Blvd, Sanandaj
Sanandaj Iran (Islamic Republic of) 66196-67761 +98 87 3328 2001 Dr.zandvakili.f.@gmail.com Kurdestan University of Medical Science. Iran (Islamic Republic of) Inclusion criteria : pregnancy , history of preeclampsia in a previous pregnancy , blood levels of vitamin D above 32 nanograms per milliliter Exclusion criteria : the risk of chronic hypertension before pregnancy , chronic kidney disease associated pulmonary and cardiovascular , immunological diseases such as lupus , the uncertainty of patient cooperation in the study , immigration or study leave. 15 years 45 years Female o14.0 , o1 Gestational [pregnancy-induced] hypertension with significant proteinuria Excl.: superimposed pre-eclampsia (O11) O14.0 Moderate pre-eclampsia O14.1 Severe pre-eclampsia Prevention Treatment - Drugs Intervention 1 : Administration of Vitamin D3, 50000 IU ,pearl intervention 2: Administration of placebo Systolic and Diastolic blood pressure. Timepoint: In initiation of study, 2 week after intervention, per 2 week to termination of pregnancy. Method of measurement: Blood pressure is measured in the sitting position by using mercury barometer. Proteinuria. Timepoint: If there is a blood pressure greater than or equal to 140/90 mm Hg. Method of measurement: laboratory kit. Preeclampsia Recognition. Timepoint: After 28 weeks of pregnancy. Method of measurement: Measurement of blood pressure by using barometer, clinical symptoms and proteinuria detection by using laboratory kit. Vice chancellor for research, Kurdistan University of Medical Sciences Approved 2016-12-26 Ethics committee of kurdistan University of Medical Science Kurdistan University of Medical Sciences, Pasdaran Blvd. Sanandaj. Sanandaj Iran (Islamic Republic of)