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IRCT20170213032560N2 IRCT 2018-07-30 Shahroud University of Medical Sciences Assessment of oral clonidine premedication on postoperative pain and agitation following cataract surgery under general anesthesia Assessment of oral clonidine premedication on postoperative pain and agitation following cataract surgery under general anesthesia 2016-10-11 anticipated 70 Complete https://irct.ir/trial/25333 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: According to randomized quadruple blocks, researcher gives a predetermined series of 70 A and B cards to the ophtalomology ward nurse who is responsible for blinding of trial. Based on this pattern participants will assign in to either intervention (A) and take clonidine or control (B) group that take placebo one hour before operation, Blinding description: Questionnaire has two parts with identical cod. Ophthalmology ward nurse, who is responsible for randomization and blinding of research, enclose the second part of questionnaire (post operative pain chart) to the patient medical record file. 3 Condition 1: H25.0 Senile incipient cataract H57.1 ocular pain. Condition 2: H25.0 Senile incipient cataract H57.1 ocular pain. Intervention 1: In intervention group, participant takes oral clonidine (Tablet 0.2 mg manufactured by Tolidaru corporation) with 30ml water one hour before operation. Ophthalmology ward nurse who is responsible for randomization supervises this procedure. Intervention 2: Control group: In controll group the patiens take 30 ml water with placebo one hour before operation. Ophthalmology ward nurse who is responsible for randomization supervises this procedure. No - There is not a plan to make this available Justification or reason for not sharing IPD is all of the writers don't agree with it
public mahsa kalantari
Seventh Tir Square - Shahrood University of Science and Technology - Vice Chancellor for Research
shahrood Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ +98 23 3239 5054 mahsa.kalantari92@yahoo.com Shahroud University of Medical Sciences scientific mahsa kalantari
Seventh Tir Square - Shahrood University of Science and Technology - Vice Chancellor for Research
shahrood Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ +98 23 3239 5054 mahsa.kalantari92@yahoo.com Shahroud University of Medical Sciences Iran (Islamic Republic of) Age: 18-85 years ASA class 1& 2 & 3 18 years 85 years Both Exclusion criteria: A history of drug abuse, antihypertensive therapy, antidepressant, anticonvulsive, beta blocker, Fluvoxamine, digoxin, dextromethorphan and every complication during surgery or anesthesia H57.1 H25.0 Ocular pain Age-related incipient cataract Treatment - Drugs Treatment - Drugs In intervention group, participant takes oral clonidine (Tablet 0.2 mg manufactured by Tolidaru corporation) with 30ml water one hour before operation. Ophthalmology ward nurse who is responsible for randomization supervises this procedure. Control group: In controll group the patiens take 30 ml water with placebo one hour before operation. Ophthalmology ward nurse who is responsible for randomization supervises this procedure. Pain, burning, foreign body sensation in the eye. Timepoint: 15min 30min 45min 60min 1h 2h 3h 4h 12h 18h 24h after operation. Method of measurement: Researcher uses 0-10 numeric pain rating scale for assessment of postoperative pain. Shahroud University of Medical Sciences Approved 2016-07-05 Ethics committee, Deputy of research, Shahroud University of Medical Sciences Deputy of research, Shahroud University of Medical Sciences, 7th of Tir square, Shahroud, Iran Shahroud Shahroud Semnan Iran (Islamic Republic of)