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IRCT2017030332853N1 IRCT 2017-03-29 Ahvaz Jundishapur University of Medical Sciences Comparison between two different routes of Furosemide administration in Patients with Pulmonary Edema A Comparison between Intravenous Furosemide and Nebulized Furosemide in Controlling the Symptoms of the Patients with Pulmonary Edema 2017-05-01 anticipated 85 Complete https://irct.ir/trial/25491 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Pulmonary edema. Intervention 1: In the intervention group the patients will receive nebulized furosemide at a dose of 1 mg furosemide for 20 minutes in 2 ml of sodium chloride 0.9%. Intervention 2: The control group the patients will receive intravenous furosemide at a dose of 1mg / kg.
public Somaye Shaabani
Farvardin Blv
Ahvaz Iran (Islamic Republic of) +98 61 3374 3009 s.shaabani@ajums.ac.ir Ahvaz Jundishapur University of Medical Sciences scientific Dr Somaye Shaabani
Farvardin Blv
Ahvaz Iran (Islamic Republic of) +98 61 3374 3009 s.shaabani@ajums.ac.ir Ahvaz Jundishapur University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients with shortness of breath during the past six hours, patients with clinical signs of pulmonary edema (tachypnea, increased lung function, use of accessory muscles, crackles, wheezes and gallop rhythm), and radiographically diagnosis of pulmonary edema. Exclusion criteria: Cardiogenic shock and blood pressure less than 90 mmHg, noncardiogenic pulmonary edema, myocardial infarction, severe heart valve disease, history of pulmonary obstructive disease, patients requiring intubation, cardiac arrhythmias, liver failure, cancer, sensitivity to Furosemide , patient’s dissatisfaction and pregnancy. 18 years 55 years Both J81.0 Acute pulmonary edema Treatment - Drugs Treatment - Drugs In the intervention group the patients will receive nebulized furosemide at a dose of 1 mg furosemide for 20 minutes in 2 ml of sodium chloride 0.9% The control group the patients will receive intravenous furosemide at a dose of 1mg / kg Dyspnea severity. Timepoint: 15,30,60 and 120 minutes after treatment. Method of measurement: Dyspnea Scale criteria. Ahvaz Jundishapur University of Medical Sciences Approved 2016-01-01 The ethics committee of Ahvaz Jundishapur University of Medical Sciences Golestan Blv Ahvaz Iran (Islamic Republic of)