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IRCT2017042333489N2 IRCT 2017-06-14 Mashhad University of Medical Sciences evaluating the effect of remote ischemic preconditioning on cadaveric transplanted kidney function evaluating the effect of remote ischemic preconditioning on cadaveric transplanted kidney function 2015-03-20 anticipated 50 Complete https://irct.ir/trial/25817 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A kidney transplantation. Intervention 1: In the intervention group who are selected randomly, the blood pressure Cuff on the right leg at the hip of receiver are closed And inflated to 200mmHg And 10 minutes at the same pressure remains.then The cuff become completely empty.And then the cuff is attached to left thigh and Up to 200 mmg inflated for 10 minutes.And then goes empty.and then The organ donation is done routinely. Intervention 2: In the control group blood pressure cuff is closed on the patient's lower extremity but it is not inflated.
public Dr Salman Soltani
Montaserieh Hospital. Golestan Street, Chmran Avenue
Mashhad Iran (Islamic Republic of) +98 51 3229 1963 soltanis@mums.ac.ir Montaserie Hospital, Mashhad University of Medical Sciences scientific ِِِDr Mahmood Tavakkoli
Montaserieh Hospital, Golestan Street, Chamran Avenue
Mashhad Iran (Islamic Republic of) +98 51 3229 1963 tavakkolim@mums.ac.ir Montaserieh,Mashhad University of Medical Sciences Iran (Islamic Republic of) (Inclusion criteria:all the cadaveric donors which are admitted to the Montaserieh hospital and enrolled in the service of a single surgical group) (Exclusion criteria:The patients ready for second transplantation;unstable cadaveric patints;the single kidney patients;the lower limbs traumatic patients;Patient dissatisfaction; when the kidneys are transplanted as en block to a recipient;Patients with advanced diabetes and vascular disease of the lower extremities; Persons under 12 years; adults over 55 years are excluded) no limit no limit Both N18 Chronic kidney disease Prevention Treatment - Drugs In the intervention group who are selected randomly, the blood pressure Cuff on the right leg at the hip of receiver are closed And inflated to 200mmHg And 10 minutes at the same pressure remains.then The cuff become completely empty.And then the cuff is attached to left thigh and Up to 200 mmg inflated for 10 minutes.And then goes empty.and then The organ donation is done routinely. In the control group blood pressure cuff is closed on the patient's lower extremity but it is not inflated Primary transplanted kidney function. Timepoint: after kidney transplantation we evaluate the urine volume every hour and check serum creatinin level 2,12 and 24 hour after sugery.and then daily upto one week and so every week upto one month. Method of measurement: after kidney transplantation we evaluate the urine volume every hour and check serum creatinin level 2,12 and 24 hour after sugery.and then daily upto one week and so every week upto one month.we calculate GFR of patient with MDRD formula. Need to dialysis again. Timepoint: after kidney transplantation we evaluate the urine volume every hour and check serum creatinin level 2,12 and 24 hour after sugery.and then daily upto one week and so every week upto one month.we calculate GFR of patient with MDRD formula. Method of measurement: after kidney transplantation we evaluate the urine volume every hour and check serum creatinin level 2,12 and 24 hour after sugery.and then daily upto one week and so every week upto one month.we calculate GFR of patient with MDRD formula. Mashhad University of Medical Sciences Approved 2014-09-23 Mashhad University of Medical Sciences Qureshi building ,University Avenue mashhad Iran (Islamic Republic of)