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IRCT2017042433622N1 IRCT 2017-05-16 Vice Chancellor for Research and Technology Effect of Fexofenadine and budesonide on the level of transcription factors: GATA-3، RORγt and FOXP3 in allergic rhinitis patients A comparison survey of GATA-3, RORγt and FOXp3 genes expression levels in peripheral blood cells of rhinitis patients, before and after treatment with fexofenadine and budesonide. 2017-05-13 anticipated 20 Complete https://irct.ir/trial/25891 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Basic scienece. 3 Rhinitis. Fexofenadine: One tablet per day Budesonide: One Puff per day.
public Ali Gorgin Karaji
School of Medicine, Daneshgah Blv. Daneshagh Square, Kermanshah
Kermnanshah Iran (Islamic Republic of) 6714869914 +98 833427461821 ali4459@gmail.com; ali4459@yahoo.com School of Medicine, Kermanshah University of Medical Sciences scientific Ali Gorgin Karaji
School of Medicine, Daneshgah Blv., Daneshgah Square, Kermanshah
Kermnanshah Iran (Islamic Republic of) 6714869914 +98 833427461821 ali4459@gmail.com; ali4459@yahoo.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: the age of man and women between 18 to 60, Signature the testimonial by the patients before entrance to the study, having rhinitis symptoms which is confirmed by specialist physician, lack of abnormality in nasal anatomy, not being suffered from: asthma, infectious disease, underlying diseases such as diabetes and chronic inflammatory diseases. In addition, pregnant women, people above 65 and those people who suffer from rhinitis because of Senility will not enter the study. Exclusion criteria: People suffering from infectious diseases or common cold and patients taking drugs other than drugs that must consume according to the research plan, during Performance of the projectو will be excluded. In addition, patients who have a fungal, viral or bacterial disease during the study and patients who do not follow the recommended instructions will be excluded. 18 years 60 years Both J30-J31 Vasomotor and allergic rhinitis and Chronic rhinitis, nasopharyngitis and pharyngitis Treatment - Drugs Fexofenadine: One tablet per day Budesonide: One Puff per day GATA3, FOXP3 and RORgt. Timepoint: Befor treatment and After one month treatment. Method of measurement: Relative expression of GATA3, FOXP3 and RORgt measured by Real-time PCR. Vice Chancellor for Research and Technology Approved 2017-02-22 Kermanshah University of Medical Sciences No. 2 bulding of KUMS, Beheshti Bolvard, Kermanshah Kermanshah Iran (Islamic Republic of)