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IRCT2017051133925N1 IRCT 2017-07-18 Vice chancellor for research, Ahvaz Jundishapur University of Medical Science Comparison the effect of Echium amoenum extract with fluoxetine on depression in menopausal women. - Comparison the effect of Echium amoenum extract with fluoxetine on depression in menopausal women. 2017-09-23 anticipated 72 Complete https://irct.ir/trial/26037 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: -. N/A Depression. Intervention 1: In the intervention group 500 mg Echium amoenum extract (capsule) will be administered daily for 8 week . Intervention 2: In The control group 20 mg fluoxetine (capsule) will be administered daily for 8 weeks .
public mitra tadayon najafabady
ahvaz medical university
ahvaz Iran (Islamic Republic of) 6135715794 +98 61 3373 8331 mitratadayon2000@yahoo.com ahvaz medical university scientific mitra tadayon najafabady
Ahvaz Jundishapur University of Medical Science and Health Services, Golestan BLV, Ahvaz
Ahvaz Iran (Islamic Republic of) 6135715794 +98 61 3373 8331 mitratadayon2000@yahoo.com Ahvaz JundiShapur University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria require that the menopausal women have amenorrhea for at least 12 months; the participants age be between 45 and 60 years and Major depression criteria based on DSM-5, According to psychiatrist verdict; patients with moderate to severe depression (14-22 with a test of Hamilton depression score). The exclusion criteria include: patients with depression that have suicidal thoughts; severe depression; Sensitivity to the fluoxetine; Getting any systemic disease such as( high blood pressure;diabetes; renal disease); Taking antidepressant medication; alcohol consumption; Use of herbal medicines for treatment of menopausal symptoms; use of Drugs that interfere with fluoxetine; surgery such as hysterectomy radical women, Vaginoplasty and artificial menopause. 45 years 60 years Female F33.1 , F3 Recurrent depressive disorder, current episode moderate.Recurrent depressive disorder, current episode severe without psychotic symptoms Treatment - Drugs Treatment - Drugs In the intervention group 500 mg Echium amoenum extract (capsule) will be administered daily for 8 week . In The control group 20 mg fluoxetine (capsule) will be administered daily for 8 weeks . Depression levels. Timepoint: 0 week, 4 week, 6 week, 8 week. Method of measurement: phycologist and Hamilton questioner. Diarrhea. Timepoint: Daily. Method of measurement: Self report. Vice chancellor for research, Ahvaz Jundishapur University of Medical Science Approved 2017-06-17 Ethics committe of Ahvaz JundiShapur University of Medical Sciences Ahvaz Jundishapur University of Medical Science and Health Services, Golestan BLV, Ahvaz Ahvaz Iran (Islamic Republic of)