]>
IRCT20170702034861N7 IRCT 2019-02-27 Kerman University of Medical Sciences The effect of anethum graveolens on pain relief from arthritis Formulation of traditional preparation of “shevid marham”and a novel topical drug delivery form the essential oil a of Dill (Anethum graveolens) and study of their effect on pain in osteoarthiritis of knee. 2019-02-20 anticipated 90 Complete https://irct.ir/trial/26529 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, randomly assigned to intervention and control groups.This method uses simple randomization models, such as using random numbers tables or using computer randomization methods, and places each referer, for example, by dropping a coin, into an intervention or control group. The implementation of this method is very simple. The disadvantages of this method are that the sample size of a group may be more than the other. One type of intervention may be given at the beginning of the study and a type of intervention at the end of the study, Blinding description: Participants and main investigators have been blinded. Patient safety is a priority, so the physician should be informed about the patient's treatment. After randomization of the patients in the intervention and control groups, the drug and placebo with the same appearance will administer to the patient who is blind to the type of medicine. The original researcher is also completely blind to the drug. Medication and placebo are provided to the physician and provided to the patient by him or her. Analysis of the results will be done by a statistics who is not necessarily the original researcher. N/A Osteoarthritis. Intervention 1: Make up to one gram twice a day, topically. Intervention 2: novel formulation of extracts and essential oils in a dose of 1 gram twice a day. Intervention 3: Sesame oil is 1 g twice a day. Intervention 4: novel formulation except active ingredient One gram twice a day. Intervention 5: diclofenac ointment One gram twice a day. Yes - There is a plan to make this available What will be shared: data of unidentifiabe of participants When: After complete data analysis and presentation of final report To whom: due to publication of data, there is no limitation Conditions: There are no limitations. Where to obtain: with main researcher How to obtain: communication through e- mail and response recieving Comments: No comment.
public Setareh Saei
Faculty of Traditional Pharmacy
Kerman Iran (Islamic Republic of) 7619813159 +98 34 3132 5020 setareh5307@gmail.com Kerman University of Medical Science scientific Fariba Sharififar
Faculty of Pharmacy,
Kerman Iran (Islamic Republic of) 7619813159 +34 31325020 fsharififar@kmu.ac.ir Kerman university of medical sciences Iran (Islamic Republic of) Primary knee osteoarthritis patients aged 40 to 80 Joint pain of osteoarthritis with or without symptoms Radiological Signs of Knee Arthritis Patients of Knee Osteoarthritis according to American Rheumatology Association criteria 40 years 80 years Both Patients with acute phase of knee arthritis Secondary osteoarthritis (such as severe joint trauma and rhomathologic diseases) Inability to keep track of enough Diabetic neuropathy M17 Osteoarthritis of knee Treatment - Drugs Treatment - Drugs Placebo Placebo Treatment - Drugs Make up to one gram twice a day, topically novel formulation of extracts and essential oils in a dose of 1 gram twice a day Sesame oil is 1 g twice a day novel formulation except active ingredient One gram twice a day diclofenac ointment One gram twice a day Pain. Timepoint: 14 day. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis Index. Percentage of active ingredients. Timepoint: Once. Method of measurement: GC-MASS. Kerman University of Medical Sciences Approved 2019-02-18 Ethics committee of kerman university of medical sciences Ibn Sina St,Tahmasebabad Crossroads Kerman Kerman Iran (Islamic Republic of)