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IRCT2017070434888N1 IRCT 2017-11-01 Vice chancellor for research of university of medical sciences of zahedan Study the effect of memantine on acute pain Study the effect of memantine on acute postoperative pain after elective hysterectomy . 2017-12-22 anticipated 60 Complete https://irct.ir/trial/26541 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Single, Purpose: Supportive, Other design features: The random blocks are divided into two groups: memantine (A) and placebo (B) This study is two-sided, and only the doctor responsible for distributing the drug knows its name, and the patient and the other physician who record the pain score and calibrate score after the operation are unaware of the type of medication used to reduce the associated bias or bouts. Intervention and evaluation of consequences are used in this way, and this way it is possible to measure objectively the outcome. N/A Condition 1: pain. Condition 2: Hysterectomy. Intervention 1: Memantine, 20 mg oral tablet, one hour before surgery. Intervention 2: placebo.
public Dr asadolah shakeri
doctor hesabi square, zahedan
zahedan Iran (Islamic Republic of) +98 54 3329 5571 keshtgarsaeed341@yahoo.com university of medical sciences of zahedan scientific Dr asadolah shakeri
doctor hesabi square, zahedan
zahedan Iran (Islamic Republic of) +98 54 3329 5571 keshtgarsaeed341@yahoo.com university of medical sciences of zahedan Iran (Islamic Republic of) Main criteria for entering the study: patient satisfaction, ages 20 to 70, selective hysterectomy surgery. Main exclusion criteria for the study of liver-renal or cardiac diseases and psychiatric illness that may disturb the patient's assessment, drug addiction or any other psychoactive substance, patient's death, and patient's lack of cooperation 20 years 70 years Female R52.0 Z90.7 Acute pain Acquired absence of genital organ(s) Treatment - Drugs Treatment - Drugs Memantine, 20 mg oral tablet, one hour before surgery placebo Pain score. Timepoint: At recovery and hours 6, 12, 24, 36 and 48 after surgery. Method of measurement: Score measured by VAS criteria. Relaxation. Timepoint: At recovery and hours 6, 12, 24, 36 and 48 after surgery. Method of measurement: Relaxation based on Ramsey's relaxation score. Drug use Required Patient. Timepoint: Within 48 hours after surgery. Method of measurement: Drug use included in patient file. Complications (nausea and vomiting). Timepoint: Within 48 hours after surgery. Method of measurement: Ask the patient for the presence or absence of nausea and vomiting. Vice chancellor for research of university of medical sciences of zahedan Approved 2017-04-16 Ethics committee of Zahedan University of Medical Sciences Zahedan Square Dr. Hesabi University of Medical Sciences campus Zahedan Iran (Islamic Republic of)