]>
IRCT20170821035831N2 IRCT 2018-02-14 Urmia Medical University Livergol Effect on Decrease of Hepatotoxicity caused by Chemotherapy Drugs  The Evaluatin of Effectiveness of the Milk Testhile for Hepatoxicity in Children with Acute Lymphoblastic Leukemia(ALL) 2017-04-19 anticipated 50 Complete https://irct.ir/trial/26957 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Single, Purpose: Treatment, Randomization description: Block, Blinding description: To randomize, the blocked randomization method will be used Given that the sample size in each group is 24, and a total of 48 people are considered, and according to its multiplicity, the permutations of the combination AAA and BBB will be used.First, all AAA BBB malformations will be written for each mode, and then all possible combinations will be mixed.Of the allocated codes, the lot number 8 (with respect to the other blocks will be 6 equal to 8 blocks will be selected) will be selected and then allocated to the alternate groups based on the selected numbers and alternate combinations. N/A Acute lymphoblastic leukaemia [ALL]. Treatment. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Dr.Farid Ghazizade
Motahari Hospital Kashani Street Urmia West Azarbaijan
Urmia Iran (Islamic Republic of) 57146-15436 +98 44 3223 7077 gazizades@yahoo.com Urmia Medical University scientific Dr.Farid Ghazizade
Motahari Hospital Kashani Street Urmia West Azarbaijan
Urmia Iran (Islamic Republic of) 57146-15436 +98 44 3223 7077 gazizades@yahoo.com Urmia Medical University Iran (Islamic Republic of) ALL diagnosis based on the criteria of the International Institute of Cancer with initial involvement of more than 20% of bone marrow Hepatotoxicity of Grade 2 and 3 in each of the following four cases based on the criteria of the International Institute of Cancer: Aminoalanine Transferase (ALT); Aspartate Aminotransferase (AST); Total Bilirubin (TB) ALL patients in the chemotherapy maintenance phase. ALL patients, 15-2 years old Patients ALL Pre Bcell, Early Pre Bcell 30 days 15 years Both Unwillingness to participate in the studyl Extra bile duct obstruction, severe liver or kidney failure, gastrointestinal obstruction, malabsorption syndrome, viral hepatitis Grade 4 hepatotoxicity Sepsis-induced hepatotoxicity Intolerance to Oral Fluoride Deny the patient to study and continue taking the medication No regular and daily intake of medication Gastritis and other complications associated with taking Lourgal History of allergy due to previous use of loroge Treatment - Drugs Treatment Liver Enzyme (AST ALT Bill Total & Direct). Timepoint: Befor Intervention , 35 and 70 days after intervention. Method of measurement: Microgram Per Litrer(for Liver Enzyme) - Miligram Per Deciliter(for Billi). Urmia Medical University Approved 2017-04-19 Urmia Medical University Motahari Hospital Kashani Street Urmia West Azarbaijan Urmia West Azarbaijan Iran (Islamic Republic of)