IRCT20170903036041N1 IRCT 2017-12-16 Vice chancellery for research Iran University of Medical Sciences Evaluation of Effectiveness of Different Dosage of Neostigmine in Combination with Metoclopramide, on Gastric Residual Volume Evaluation of Effectiveness of Different Dosage of Neostigmine in Combination with Metoclopramide, on Gastric Residual Volume, in Enteral Nutrition, in Hospitalized Patients in Intensive Care Unit 2017-06-22 anticipated 165 Complete https://irct.ir/trial/27067 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Traumatized patients divided into three groups A, B and C using block randomized method. In this study a person who is not in the study process after the admission of the patient, allocated the relevant intervention to each patient with the relevant block and notifies the director of the research team, Blinding description: This is a double blind study that patients or their companions after verifying the informed consent of the study, will be blind the type of intervention. Physicians and carers of patients which examines the clinical status of patients will be blind to the type of intervention that patients are taking. 2-3 Gastric residual volume. Intervention 1: (Gold standard group): Metoclopramide will be prescribed five milligrams in every eight hours by IV.slow method during one minute. In addition, one milligram of Neostigminedose in dilute solution of 100 cc Normal Saline and infusion takes in time 60 minut. Intervention 2: (Intervention group 2): Metoclopramide will be prescribed five milligrams in every eight hours by IV.slow method during one minute. In addition, two milligrams of Neostigmine dose in dilute solution of 100 cc Normal Saline and infusion takes in time 60 mi. Intervention 3: (Intervention group 1): Metoclopramide will be prescribed five milligrams in every eight hours by IV.slow method during one minute. In addition, one and a half milligrams of Neostigmine dose in dilute solution of 100 cc Normal Saline and infusion takes in. Undecided - It is not yet known if there will be a plan to make this available