IRCT20170925036401N2 IRCT 2017-12-22 Deputy of Research of Guilan University of Medical Sciences effect of eptifibatide and reteplase on primary angioplasty outcomes Comparison of the efficacy of intracoronary and intravenous Eptifibatide and intracoronary Retaplase in thrombus aspiration in patients undergoing Primary percutaneous coronary interventions (PPCI); Randomized clinical trial study) 2017-11-21 anticipated 160 Complete https://irct.ir/trial/27220 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Acute Myocardial Infarction. All patients will receive Emergency PCI treatment. Patients will receive 300 mg of chewing aspirin and 600 mg of Clopidogrel maintenance dose prior to the procedure before transferring to the catheterism room. In the first group, the patients undergo thrombus suction after the wiring , and then the stent is embedded.In the second group, the patients undergo thrombus suction after wiring , then receive 180μg / kg intra coronary bolus eptifibatide. Intra coronary eptifibatide will be injected 2 times with 10 minutes interval and then the stent will be embedded.In the third group, patients undergo thrombus suction after wiring , and then 6 mg intracoronary reteplase is injected and the stent will be embedded.In the fourth group, the patients undergo thrombus suction after wiring , then receive 180μg / kg intravenous bolus eptifibatide during 18 hours in the ward.After the procedure angiography report for TIMI blush grade and corrected TIMI frame count will be seen.All patients will be treated with a maintenance dose of 75 mg clopidogrel daily for one year and 300 mg of aspirin for 30 days and then 100 mg..