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IRCT20171016036817N1 IRCT 2017-12-22 Zahedan University of Medical Sciences Effect of Acetaminophen and Dexamethasone on agitation in tonsillectomy children Study of Acetaminophen and Dexamethasone effects on agitation in children undergoing tonsillectomy 2017-12-21 anticipated 140 Complete https://irct.ir/trial/27428 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The randomization and the entry of the statistical community into each intervention or control group will be based on the selection of colored papers, so that we will have four colors of blue, green, yellow and red papers for the sample size. Those who take the blue paper will enter the intervention group, those who take the green paper will go into the control group with the acetaminophen placebo, those who take the yellow paper will go into the control group with the dexamethasone placebo, and the those who take the red paper will enter the control group with the Both the placebo, Blinding description: Each member of the control and intervention groups will not aware of the fact that they will receive the medication or placebo. The statistician will also analyze the data with coding so that he will also not aware that which data is related to the control group and which data will be related to the intervention group. 3 Tonsil's inflammation. Intervention 1: Intervention Group 1:Receiving Dexamethasone and placebo acetaminophen (Dexamethasone At the request of the hospital's drugstore intravenously 0.2 mg / kg in addition to 0.25 mg / kg of syrup with strawberry flavor). Intervention 2: Intervention group2: Receiving Acetaminophen and Dexamethasone placebo (20 mg per kg of acetaminophen syrup At the request of the hospital's drugstore with 0.5 ml / kg of normal saline). Intervention 3: Intervention group3: Receiving Acetaminophen and Dexamethasone (20 mg / kg acetaminophen syrup At the request of the hospital's drugstore with 0.2 mg / kg intravenous dexamethasone At the request of the hospital's drugstore). Intervention 4: Control group: Receiving dexamethasone placebo and acetaminophen placebo (normal saline 0.5 ml / kg plus 0.25 mg / kg of syrup with strawberry flavor). Undecided - It is not yet known if there will be a plan to make this available
public Maryam Haghighatjooy
Zahedan University of Medical Sciences , Dr hesabi sq.
Zahedan Iran (Islamic Republic of) 9816743463 +98 54 3329 5715 m.haghighatjoo@zaums.ac.ir Zahedan University of Medical Sciences scientific Gholamali Dashti
Zahedan University of Medical Sciences , Dr hesabi sq.
Zahedan Iran (Islamic Republic of) 9816743463 +98 54 3329 5715 dr.dashti@zaums.ac.ir Zahedan University of Medical Sciences Iran (Islamic Republic of) Parents are satisfied with entering the study All children aged 2 to 7 years undergoing tonsillectomy 2 years 7 years Both Those who have taken previous medications (all previous medications should be removed within 2 hours before the surgery) C09.9 Tonsil, unspecified Treatment - Drugs Treatment - Drugs Treatment - Drugs Placebo Intervention Group 1:Receiving Dexamethasone and placebo acetaminophen (Dexamethasone At the request of the hospital's drugstore intravenously 0.2 mg / kg in addition to 0.25 mg / kg of syrup with strawberry flavor) Intervention group2: Receiving Acetaminophen and Dexamethasone placebo (20 mg per kg of acetaminophen syrup At the request of the hospital's drugstore with 0.5 ml / kg of normal saline) Intervention group3: Receiving Acetaminophen and Dexamethasone (20 mg / kg acetaminophen syrup At the request of the hospital's drugstore with 0.2 mg / kg intravenous dexamethasone At the request of the hospital's drugstore) Control group: Receiving dexamethasone placebo and acetaminophen placebo (normal saline 0.5 ml / kg plus 0.25 mg / kg of syrup with strawberry flavor) Agitation. Timepoint: Prior to admission, pain is measured by face scale and children's agitation will measured by the Richmond Agitation Sedation Score. The two cases are also measured after admission and receiving drugs in the PICU, as well as 10, 20, and 30 minutes after extubation of the tube tract. (0: vigilant and calm, 1: restless, 2: disturbed, 3: very disturbed and 4: controversy and fights). Method of measurement: pain is measured by face scale and children's agitation will measured by the Richmond Agitation Sedation Score. Zahedan University of Medical Sciences Approved 2017-06-18 Ethics committee of Zahedan University of Medical Sciences Zahedan University of Medical Sciences , Dr hesabi sq. Zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)