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IRCT138809282885N1 IRCT 2017-06-01 Vice Chancellor for Research, Qazvin University of Medical Sciences Effect of surgical periodontal therapy on gingival cervicular fluid and salivary concentration of L-Plastin Effect of surgical periodontal therapy on gingival cervicular fluid and salivary concentration of L-Plastin in patients with chronic peridontitis 2016-10-01 anticipated 40 Complete https://irct.ir/trial/2757 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Chronic periodontitis. Intervention 1: In case group after oral hygiene instruction and scaling & root planng after one month flap surgery will done in quadrant that needs surgery. Intervention 2: In control group no intervention will done.
public Dr Asieh Mozaffari
Qazvin Medical Science , Bahonar blvd, Qazvin
Qazvin Iran (Islamic Republic of) 5981134197 +98 28 3323 9256 assaiehmozaffari@yahoo.com Qazvin Dental School scientific Dr Shadi Assareh
Bahonar blvd, Qazvin
Qazvin Iran (Islamic Republic of) 5981134197 +98 28 3323 9256 drshadi.assareh@gmail.com Qazvin Dental School Iran (Islamic Republic of) Inclusion criteria: The control group was the people that They had no history of periodontitis ; had more than 20 teeth; They exhibited no sites with > 3 mm probing pocket depth ;No sites with> 1 mm clinical attachment loss; as well as no radiographic evidence of alveolar bone loss. The chronic periodontitis group had more than 20 teeth; had probing pocket depth ≥ 5 mm & clinical attachment loss of ≥ 3 mm, which was commensurate with the amount of plaque accumulation with radiographic evidence of alveolar bone in at least two quadrant of four quadrant in which at least two teeth in each quadrant have clinical attachment loss & bone loss. Exclusion criteria:chemotherapy; pregnancy; lactation; HIV; systemic disease like respiratory & cardiovascular disease; getting antibiotic & other drugs within 4 months ago; getting periodontal therapy in the past. 18 years 65 years Both KO5.3 Chronic pericoronitis Periodontitis: NOS complex simplex Treatment - Surgery N/A In case group after oral hygiene instruction and scaling & root planng after one month flap surgery will done in quadrant that needs surgery. In control group no intervention will done L plastin concentration. Timepoint: Baseline, one month after oral hygiene instruction & scaling & root planing and one month after completion of flap surgeries. Method of measurement: Analysis done with ELIZA , picogram /ml. Probing depth. Timepoint: Baseline, One month after oral hygiene instruction and scaling & root planing and one month after completion of flap surgeries. Method of measurement: Milimeter with periodontal probe. Attachment loss. Timepoint: Baseline,One month after oral hygiene instruction and scaling & root planing and one month after completion of flap surgeries. Method of measurement: Milimeter with periodontal probe. Plaque index. Timepoint: Baseline, One month after oral hygiene instruction and scaling & root planing and one month after completion of flap surgeries. Method of measurement: Oraly plaque index. Bleeding on probing. Timepoint: Baseline, One month after oral hygiene instruction and scaling & root planing and one month after completion of flap surgeries. Method of measurement: Dichotomous measurement of bleeding on probing. Vice Chancellor for Research, Qazvin University of Medical Sciences Approved 2016-05-25 Ethics Committee Qazvin Medical Science School Bahonar blvd, Qazvin Qazvin Iran (Islamic Republic of)