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IRCT20171105037246N2 IRCT 2018-03-04 Vice Chancellor For Research Shahid Sadoughi University of Medical Sciences of Yazd Effect of intravenous aminophylline on renal function of brain injury patients with acute renal failure Survey of the effect of intravenous aminophylline on renal function of brain injury patients with acute renal failure admitted to the intensive care unit 2017-07-23 anticipated 50 Complete https://irct.ir/trial/27601 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: The randomization of study groups will be done by using table of random numbers, Randomization description: The randomization of patients will be done by using table of random numbers with the obtained numbers, patients will be assigned to two groups of intervention and control, Blinding description: This is a double-blinded study and Researcher and patients are kept unaware of intervention in each group. 3 Condition 1: Brain injury patients with acute renal failure. Condition 2: Acute renal failure. Intervention 1: In the intervention group, the urine output, BUN and creatinine of the patients, 24 hours before the study, will be measured and recorded by the researcher assistant. Then, an Aminophylline dose of 0.2 mg / kg / h is started as an intravenous infusion acc. Intervention 2: The Patients in the control group received normal saline 0.9% in the same dose received in the intervention group and their renal function scales such as the intervention group will be measured. Undecided - It is not yet known if there will be a plan to make this available
public Manijeh Shahriary Kalantary
SHohadaye Gomnam Boulevard, Safayeh, Yazd
Yazd Iran (Islamic Republic of) 8914656548 +98 35 3187 2200 m_kalan13@iauyazd.ac.ir Islamic Azad University of Yazd scientific Manijeh Shahriary Kalantary
SHohadaye Gomnam Boulevard, Safayeh, Yazd
Yazd Iran (Islamic Republic of) 8914656548 +98 35 3187 2200 m_kalan13@iauyazd.ac.ir Islamic Azad University of Yazd Iran (Islamic Republic of) Brain injury patients after the stabilization of hemodynamic symptoms from both sexes patients with acute renal failure after admission to the intensive care unit 18-65 years old 18 years 65 years Both Patients with unstable hemodynamic conditions Contraindications for aminophylline History of seizure History of arrhythmia Patients with a history of renal dysfunction S06.2 N17 Diffuse traumatic brain injury Acute kidney failure Treatment - Drugs Placebo In the intervention group, the urine output, BUN and creatinine of the patients, 24 hours before the study, will be measured and recorded by the researcher assistant. Then, an Aminophylline dose of 0.2 mg / kg / h is started as an intravenous infusion acc The Patients in the control group received normal saline 0.9% in the same dose received in the intervention group and their renal function scales such as the intervention group will be measured. Blood Urea Nitrogen. Timepoint: 24 hours before and after intervention. Method of measurement: mg/dl. Urine output. Timepoint: 24 hours before and after intervention. Method of measurement: Ml. Creatinin. Timepoint: 24 hours before and after intervention. Method of measurement: mg/dl. Vice Chancellor For Research Shahid Sadoughi University of Medical Sciences of Yazd Approved 2017-04-26 Ethics committee of Yazd Shahid Sadoughi University of Medical Sciences The central building of Shahid Sadoughi University of Medical Sciences, Bahonar Square, Yazd Yazd Yazd Iran (Islamic Republic of)