IRCT201104032892N1 IRCT 2011-04-03 Vice chancellor for research, Islamic Azad University of karaj branch Effect of diet and exercise program to improve polycystic ovary syndrome (PCOS) Comparison of effects of diet and exercise program to improve clinical symptoms and laboratory tests in obese women with polycystic ovary syndrome (PCOS) 2010-01-15 anticipated 50 Complete https://irct.ir/trial/2777 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 polycystic ovary syndrome. Intervention 1: Experimental group: Diet and exercise program Diet plan: at the beginning of study a check list prepared for each individual and weekly regimen recommended separately based on feeding patterns and individual facilities. The method of regimen calculation based on total energy for each individual (TEE). We set the countable energy for reducing weight 1000 grams per week. Reduced the amount of energy and some energy into the physical activity to lose weight fraction are obtained. The combination of energy, including 40% carbohydrate, 30% fat (less than 8% saturated fatty acids was) and 30% protein is high physiological value. Fitness program: exercise sessions that included 24 meeting which duration per session was variable according to the program. For improving aerobic energy system and strengthen cardiovascular system a series exercises (slow jogging) will be used. At the beginning of the first practice sessions will be used slow intensity aerobic exercise. The first training sessions with 5 minutes of times, and 50 percent of maximum heart rate of cholera in the form alternating between resting half the time repeating the exercise. In each session we were trying to follow the principle of overload for improving cardiovascular efficiency. In higher stages (after the fifth session) of the repetition of exercises with some 60 percent of maximum heart rate is achieved. Of the ninth session, training intensity reaches to 70 percent of maximum heart rate and in last sessions with 80 percent maximum heart rate do their exercise. In each session, subjects in the first 10 minutes to warm the body and also the final 10 minutes of cooling down exercises and return to the initial state. Intervention 2: For controls group: The standard drugs Diane: from fifth Day of cycle for 21 days every night, once a day Spironolactone: 25 mg twice a day.