IRCT20151012024490N2 IRCT 2018-01-01 Gorgan University of Medical Sciences Effectiveness of Sambucus Ebulus leaf extract ointment in treatment results of Cutaneous Leishmaniasis Comparing the effectiveness of Sambucus Ebulus leaf extract ointment and placebo, in treatment results of Cutaneous Leishmaniasis; A double blind clinical trial 2017-12-06 anticipated 110 Complete https://irct.ir/trial/27905 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be randomly divided into 2 groups; cases and controls based on Simple Random Allocation (random numbers table), Blinding description: All cases and controls will get an ointment which looked like in shape, color and smell. And each patient will get an unique code. 3 Cutaneous Leishmaniasis. Intervention 1: Sambucus Ebulus leaf extract ointment. In order to prepare the ointment, a 5% extract of the plant leaves in vaseline (and liquid paraffin) will be used. This drug will be made at Mazandaran University of Medical Sciences. The ointment will be used twice a day. First the lesion should be washed with water. After drying, a thin layer of ointment should be used and the area should be kept dry for about two hours. It is forbidden to use other medications at the treatment time. Intervention 2: Placebo ointment contains the base compound (Vaseline and liquid paraffin) that will be similar to the drug in shape and smell and only the active ingredient will be absent. This placebo will be made at Mazandaran University of Medical Sciences. The ointment will be used twice a day. First the lesion should be washed with water. After drying, a thin layer of ointment should be used and the area should be kept dry for about two hours. It is forbidden to use other medications at the treatment time. Undecided - It is not yet known if there will be a plan to make this available