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IRCT20131012014988N3 IRCT 2018-04-26 Reasearch Deputy, Tabriz University of Medical Sciences efficacy of airway clearance therapy (ACT) on short time outcome of cystic fibrosis patients Evaluating the efficacy of airway clearance therapy (ACT) on short time outcome of cystic fibrosis patients in tabriz chlidren’s hospital 2017-03-21 anticipated 60 Complete https://irct.ir/trial/28650 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A cystic fibrosis. Intervention 1: Intervention group: In addition to antibiotic therapy and conventional chest physiotherapy, patients underwent NIV with BIPAP (NIV on days 2, 4 and 6 admitted for 2 hours) and PEP (on the second, fourth and sixth days on admission for 30 minutes) Placed. Intervention 2: Control group: The control group will be treated with antibiotics and conventional chest physiotherapy only. Ultimately, spirometry will be performed once per hospitalization and one day on discharge, and their differences will be compared with FEV1 and FVC. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Nemat Bilan
Pediatric Health Research Center, Children Hospital, Sheshgelan street, Tabriz, Iran.
Tabriz Iran (Islamic Republic of) 5136735886 +98 41 3526 2265 phrc_mb@tbzmed.ac.ir Pediatric Health Research Center, Tabriz University of Medical Sciences scientific Nemat Bilan
Pediatric Health Research Center, Tabriz Children Hospital, Sheshgelan Street, Tabriz, Iran.
TABRIZ Iran (Islamic Republic of) 5136735886 +98 41 3526 2265 phrc_mb@tbzmed.ac.ir Pediatric Health Research Center, Tabriz University of Medical Sciences Iran (Islamic Republic of) • Patients with CF diagnosis• Patients aged 5 to 14 years• Patients with exacerbation of lung disease with FEV1 = 20-70% in initial spirometry when admitted 5 years 14 years Both • Patients with reluctance to continue participating in the study• Patients who can not be traced to a cause such as death, transference to another city, etc. during the study period.• Patients who do not have adequate compilation to continue treatment. E84.0 Cystic fibrosis with pulmonary manifestations Treatment - Other Placebo Intervention group: In addition to antibiotic therapy and conventional chest physiotherapy, patients underwent NIV with BIPAP (NIV on days 2, 4 and 6 admitted for 2 hours) and PEP (on the second, fourth and sixth days on admission for 30 minutes) Placed Control group: The control group will be treated with antibiotics and conventional chest physiotherapy only. Ultimately, spirometry will be performed once per hospitalization and one day on discharge, and their differences will be compared with FEV1 and FVC. Forced expiratory volume in the first second. Timepoint: In the second and last day of the admission. Method of measurement: By using spirometry device. FEV1/FVC. Timepoint: In the second and last day of the admission. Method of measurement: By using spirometry device. Peak expiratory flow. Timepoint: In the second and last day of the admission. Method of measurement: By using peak flow-meter device. Number of Exacerebration within six months. Timepoint: within six months. Method of measurement: Cheklist. Reasearch Deputy, Tabriz University of Medical Sciences Approved 2017-12-04 Regional Ethics Committee, Office of the Vice Chancellor for Research, Tabriz University of Medical تبریز-خیابان دانشگاه-ساختمان مرکزی شماره 2 دانشگاه علوم پزشکی تبریز- طبقه سوم-معاونت تحقیقات و فن آوری دانشگاه علوم پزشکی تبریز tabriz East Azarbaijan Iran (Islamic Republic of)